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Articles Published Processes
9/18/2021 9:35:02 AM | Browse: 456 | Download: 947
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Received |
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2021-02-27 22:53 |
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Peer-Review Started |
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2021-02-27 22:58 |
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To Make the First Decision |
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Return for Revision |
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2021-04-20 01:12 |
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Revised |
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2021-04-21 13:53 |
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Second Decision |
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2021-08-24 03:23 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-24 08:47 |
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Articles in Press |
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2021-08-24 08:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-09-03 22:03 |
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Typeset the Manuscript |
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2021-09-17 01:12 |
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Publish the Manuscript Online |
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2021-09-18 09:35 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Review |
| Article Title |
Effects of storage media, supplements and cryopreservation methods on quality of stem cells
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ozgur Dogus Erol, Burcu Pervin, Mehmet Emin Seker and Fatima Aerts-Kaya |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Scientific and Technological Research Council of Turkey (TÜBİTAK) |
118S738 |
| the Scientific and Technological Research Council of Turkey (TÜBİTAK) |
219S675 |
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| Corresponding Author |
Fatima Aerts-Kaya, MD, PhD, Assistant Professor, Department of Stem Cell Sciences, Hacettepe University Graduate School of Health Sciences, 4 Reymonta Street, Ankara 06100, Türkiye. fatimaaerts@yahoo.com |
| Key Words |
Cryoprotective agents; Dimethyl sulfoxide; Hematopoietic stem cells; Mesenchymal stromal/stem cells; Induced pluripotent stem cells |
| Core Tip |
The manuscript is an overview of current cryopreservation protocols used for cold storage of hematopoietic stem cells, mesenchymal stem cells and induced pluripotent stem cells. Although dimethyl sulfoxide (DMSO) is commonly used in cryopreservation of cell lines, primary cells and stem cells, the use of DMSO has been associated with certain toxicity, both directly on the cells, as well as upon infusion with the stem cell product. As a result of this many groups have undertaken efforts to find suitable replacements for DMSO, that are equally potent, but less toxic. In this review we summarize the current status quo of stem cell freezing protocols, we describe the most commonly used cryoprotective agents and their effects on stem cells and stem cell function. |
| Publish Date |
2021-09-18 09:35 |
| Citation |
Erol OD, Pervin B, Seker ME, Aerts-Kaya F. Effects of storage media, supplements and cryopreservation methods on quality of stem cells. World J Stem Cells 2021; 13(9): 1197-1214 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i9/1197.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i9.1197 |
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