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Articles Published Processes
8/20/2021 5:46:25 AM | Browse: 394 | Download: 781
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Received |
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2021-02-28 08:08 |
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Peer-Review Started |
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2021-02-28 08:10 |
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To Make the First Decision |
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Return for Revision |
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2021-04-19 20:06 |
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Revised |
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2021-05-02 07:38 |
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Second Decision |
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2021-07-07 12:55 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-07 14:09 |
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Articles in Press |
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2021-07-07 14:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-16 21:37 |
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Typeset the Manuscript |
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2021-08-17 06:49 |
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Publish the Manuscript Online |
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2021-08-20 05:46 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Central nervous system tumors and three-dimensional cell biology: Current and future perspectives in modeling
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zaki Abou-Mrad, Jolie Bou Gharios, Maya M Moubarak, Ahmad Chalhoub, Charbel Moussalem, Hisham F Bahmad and Wassim Abou-Kheir |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wassim Abou-Kheir, MSc, PhD, Associate Professor, Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Bliss St., DTS Bldg, Beirut 1107-2020, Lebanon. wa12@aub.edu.lb |
| Key Words |
Central nervous system tumors; Glioblastoma; Three-dimensional modelling; Spheroids; Organoids |
| Core Tip |
Central nervous system tumors present multiple challenges in treatment and patient prognosis. Glioblastoma, the most common adult brain tumor, remains one of the most lethal malignant brain tumors even at the current standard of care. Traditional in vitro culturing is limited in recapitulating the features of the in vivo tumors. We herein discuss recent advancements in three-dimensional culturing for tumor modeling, their advantages, and limitations, in addition to future perspectives. |
| Publish Date |
2021-08-20 05:46 |
| Citation |
Abou-Mrad Z, Bou Gharios J, Moubarak MM, Chalhoub A, Moussalem C, Bahmad HF, Abou-Kheir W. Central nervous system tumors and three-dimensional cell biology: Current and future perspectives in modeling. World J Stem Cells 2021; 13(8): 1112-1126 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i8/1112.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i8.1112 |
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