Publication Name	World Journal of Immunology
Manuscript ID	6511
Country	Spain

Received	2013-10-22 11:28
Peer-Review Started	2013-10-22 16:21
To Make the First Decision	2013-12-02 11:44
Return for Revision	2013-12-04 09:52
Revised	2013-12-05 03:51
Second Decision	2014-02-18 11:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-02-18 12:28
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-25 17:57
Publish the Manuscript Online	2014-03-26 14:31

ISSN	2219-2824 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Nutrition & Dietetics
Manuscript Type	Review
Article Title	Circulating immune cell activation and diet: A review on human trials
Manuscript Source	Invited Manuscript
All Author List	Gemma Chiva-Blanch and Ramon Estruch
Funding Agency and Grant Number
Corresponding Author	Ramon Estruch, MD, PhD, Department of Internal Medicine, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain. restruch@clinic.ub.es
Key Words	Mediterranean diet; Immune cell activation; Leukocyte adhesion; Inflammation; Fatty acids; Fruits; Vegetables; Polyphenols; Cardiovascular disease; Cancer
Core Tip	Immune cell activation is involved in several pathophysiological processes that play a crucial role in the appearance of cardiovascular disease or cancer. The aim of this review is to update the knowledge of the modulation of immune cell activation by different dietary patterns. A westernized high-saturated fat high-carbohydrate diet is positively associated with low-grade inflammation, but a Mediterranean diet, rich in vegetables and fruits decrease the levels of cellular and circulating inflammatory biomarkers thereby reducing the risk of related chronic diseases.
Publish Date	2014-03-26 14:31
Citation	Chiva-Blanch G, Estruch R. Circulating immune cell activation and diet: A review on human trials. World J Immunol 2014; 4(1): 12-19
URL	http://www.wjgnet.com/2219-2824/full/v4/i1/12.htm
DOI	http://dx.doi.org/10.5411/wji.v4.i1.12

Full Article (PDF)	WJI-4-12.pdf
Full Article (Word)	WJI-4-12.doc
Manuscript File	6511-Review.docx
Answering Reviewers	6511-Answering reviewers.pdf
Copyright License Agreement	6511-Copyright assignment.pdf
Peer-review Report	6511-Peer review(s).pdf
Scientific Editor Work List	6511-Scientific editor work list.doc