Publication Name	World Journal of Gastroenterology
Manuscript ID	6513
Country	China

Received	2013-10-22 11:32
Peer-Review Started	2013-10-22 18:44
To Make the First Decision	2013-11-13 13:51
Return for Revision	2013-11-14 10:57
Revised	2013-11-24 23:29
Second Decision	2014-01-20 17:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-20 18:05
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-19 08:01
Publish the Manuscript Online	2014-05-28 11:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Topic Highlights
Article Title	Management of chronic hepatitis B infection: Current treatment guidelines, challenges, and new developments
Manuscript Source	Invited Manuscript
All Author List	Ceen-Ming Tang, Tung On Yau and Jun Yu
Funding Agency and Grant Number	Funding Agency Grant Number Collaborative Research Fund of the Research Grant Council Hong Kong CUHK3/CRF/12R Collaborative Research Fund of the Research Grant Council Hong Kong HKU3/CRF11R National Basic Research Program of China 2013CB531401 CUHK Focused Investments Scheme B to HY Lan Theme-based Research Scheme of the Hong Kong Research Grants Council T12-403-11
Corresponding Author	Jun Yu, MD, PhD, Professor, Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, LKS Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China. junyu@cuhk.edu.hk
Key Words	Chronic hepatitis B virus infection; National institute for health and care excellence; Treatment guidelines; Interferon; Pegylated interferon; Nucleos(t)ide analogues; Antiviral resistance; Rescue therapy; Clinical trials
Core Tip	This article summarizes the different indications for treatment, and systematically reviews the evidence for the efficacy of various antiviral agents. It further discusses the shortcomings of current guidelines, use of rescue therapy in drug-resistant strains of hepatitis B virus, and highlights the promising clinical trials for emerging therapies in the pipeline. This concise overview presents an updated practical approach to guide the clinical management of chronic hepatitis B.
Publish Date	2014-05-28 11:45
Citation	Tang CM, Yau TO, Yu J. Management of chronic hepatitis B infection: Current treatment guidelines, challenges, and new developments. World J Gastroenterol 2014; 20(20): 6262-6278
URL	http://www.wjgnet.com/1007-9327/full/v20/i20/6262.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i20.6262

Full Article (PDF)	WJG-20-6262.pdf
Full Article (Word)	WJG-20-6262.doc
Manuscript File	6513-Review.docx
Answering Reviewers	6513-Answering reviewers.pdf
Copyright License Agreement	6513-Copyright assignment.pdf
Peer-review Report	6513-Peer review(s).pdf
Scientific Editor Work List	6513-Scientific editor work list.doc