Publication Name	World Journal of Gastroenterology
Manuscript ID	6515
Country	Italy

Received	2013-10-22 11:45
Peer-Review Started	2013-10-22 18:54
To Make the First Decision	2014-01-09 13:44
Return for Revision	2014-01-10 10:39
Revised	2014-02-20 21:24
Second Decision	2014-05-05 08:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-05-05 09:46
Articles in Press	2014-05-23 10:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-13 15:55
Publish the Manuscript Online	2014-07-26 13:36

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Topic Highlights
Article Title	Cytokinome profile evaluation in patients with hepatitis C virus infection
Manuscript Source	Invited Manuscript
All Author List	Francesca Capone, Eliana Guerriero, Giovanni Colonna, Patrizia Maio, Alessandra Mangia, Giuseppe Castello and Susan Costantini
Funding Agency and Grant Number
Corresponding Author	Susan Costantini, PhD, Centro Ricerche Oncologiche di Mercogliano, IstitutoNazionale per lo Studio e la CuradeiTumori “Fondazione Giovanni Pascale”, IRCCS, Via AmmiraglioBianco, 83013 Mercoglicano, Italy. s.costantini@istitutotumori.na.it
Key Words	Cytokinome; Hepatitis C virus; Cirrhosis; Type 2 diabetes; Hepatocellular carcinoma; Interactome; Systems biology
Core Tip	In this review we report the usefulness of cytokinome profiling in improving our understanding of the role cytokines play in the evolution of chronic inflammatory processes leading to cancer. The serum levels of cytokines were evaluated in patients with hepatitis C virus infection-related liver diseases in the presence and absence of either hepatocellular carcinoma or type 2 diabetes. In addition, the complex interaction network, between the significant cytokines and their metabolic pathways, was studied using bioinformatics and systems biology approaches.
Publish Date	2014-07-26 13:36
Citation	Capone F, Guerriero E, Colonna G, Maio P, Mangia A, Castello G, Costantini S. Cytokinome profile evaluation in patients with hepatitis C virus infection. World J Gastroenterol 2014; 20(28): 9261-9269
URL	http://www.wjgnet.com/1007-9327/full/v20/i28/9261.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i28.9261

Full Article (PDF)	WJG-20-9261.pdf
Full Article (Word)	WJG-20-9261.doc
Manuscript File	6515-Review.doc
Answering Reviewers	6515-Answering reviewers.pdf
Copyright License Agreement	6515-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6515-Language certificate.pdf
Peer-review Report	6515-Peer review(s).pdf
Scientific Editor Work List	6515-Scientific editor work list.pdf