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Articles Published Processes
9/15/2021 10:23:34 AM | Browse: 429 | Download: 637
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Received |
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2021-02-28 17:42 |
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Peer-Review Started |
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2021-02-28 17:53 |
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To Make the First Decision |
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Return for Revision |
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2021-04-20 23:12 |
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Revised |
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2021-05-02 18:13 |
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Second Decision |
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2021-08-18 03:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-18 07:44 |
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Articles in Press |
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2021-08-18 07:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-09-01 10:22 |
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Publish the Manuscript Online |
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2021-09-15 10:23 |
ISSN |
2220-3206 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Psychiatry |
Manuscript Type |
Systematic Reviews |
Article Title |
Deep brain stimulation for obsessive-compulsive disorder: A systematic review of worldwide experience after 20 years
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Manuscript Source |
Invited Manuscript |
All Author List |
Lorea Mar-Barrutia, Eva Real, Cinto Segalás, Sara Bertolín, José Manuel Menchón and Pino Alonso |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Carlos III Health Institute |
PI16/00950 |
Carlos III Health Institute |
PI18/00856 |
FEDER funds (‘A way to build Europe’) |
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Corresponding Author |
Pino Alonso, PhD, Senior Researcher, OCD Clinical and Research Unit, Department of Psychiatry, Hospital de Bellvitge, C/Feixa Llarga s/n, Barcelona 08907, Spain. mpalonso@bellvitgehospital.cat |
Key Words |
Deep brain stimulation; Obsessive-compulsive disorder; Predictors of response; Side effects; Short-term; Long-term |
Core Tip |
This systematic review describes worldwide experience in the use of deep brain stimulation (DBS) in severe resistant patients with obsessive-compulsive disorder over the last twenty years, comparing short-term (ST) and long-term (LT) response to the treatment (in 230 and 155 patients respectively). Both ST and LT studies report similar, stable reductions in severity of around 47%, although the number of patients who met the criteria for response was significantly higher in the LT studies (60.6% vs 70.7%). DBS is a safe and well-tolerated technique, since most side effects are mild and reversible on adjusting stimulation parameters. However, no clear predictors of response can be established at present. |
Publish Date |
2021-09-15 10:23 |
Citation |
Mar-Barrutia L, Real E, Segalás C, Bertolín S, Menchón JM, Alonso P. Deep brain stimulation for obsessive-compulsive disorder: A systematic review of worldwide experience after 20 years. World J Psychiatr 2021; 11(9): 659-680 |
URL |
https://www.wjgnet.com/2220-3206/full/v11/i9/659.htm |
DOI |
https://dx.doi.org/10.5498/wjp.v11.i9.659 |
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