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Articles Published Processes
10/22/2021 1:53:28 PM | Browse: 470 | Download: 992
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Received |
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2021-02-28 20:51 |
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Peer-Review Started |
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2021-02-28 21:00 |
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To Make the First Decision |
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Return for Revision |
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2021-05-02 23:49 |
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Revised |
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2021-05-12 16:42 |
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Second Decision |
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2021-09-17 03:30 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-09-19 09:05 |
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Articles in Press |
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2021-09-19 09:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-10-20 01:26 |
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Publish the Manuscript Online |
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2021-10-22 13:53 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Serum zonulin levels in patients with liver cirrhosis: Prognostic implications
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Theodoros A Voulgaris, Dimitrios Karagiannakis, E Hadziyannis, Spilios Manolakopoulos, Georgios P Karamanolis, George Papatheodoridis and John Vlachogiannakos |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
John Vlachogiannakos, MD, PhD, Professor, Academic Department of Gastroenterology and Hepatology, Medical School of National and Kapodistrian University of Athens, General Hospital of Athens “Laiko”, 17 Agiou Thoma Street, Athens 11527, Greece. jvlachog@hotmail.com |
| Key Words |
Zonulin; Cirrhosis; Intestinal barrier; Bacterial translocation; Decompensation; Permeability |
| Core Tip |
Zonulin is a protein that appears to play a significant role in gut barrier integrity. Increased zonulin levels and deregulation of intestinal permeability have been demonstrated in patients suffering from celiac disease or type 2 diabetes. However, the role of zonulin as a promoting factor of intestinal barrier disruption in patients with liver cirrhosis has not been studiedadequately. We evaluated serum zonulin levels in patients with different stages of advanced liver disease. According to our findings, serum zonulin levels are increased in patients with more advanced liver disease and are independently associated with progression to decompensation. |
| Publish Date |
2021-10-22 13:53 |
| Citation |
Voulgaris TA, Karagiannakis D, Hadziyannis E, Manolakopoulos S, Karamanolis GP, Papatheodoridis G, Vlachogiannakos J. Serum zonulin levels in patients with liver cirrhosis: Prognostic implications. World J Hepatol 2021; 13(10): 1394-1404 |
| URL |
https://www.wjgnet.com/1948-5182/full/v13/i10/1394.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v13.i10.1394 |
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