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Articles Published Processes
11/25/2021 8:31:19 AM | Browse: 443 | Download: 1059
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Received |
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2021-03-05 09:36 |
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Peer-Review Started |
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2021-03-05 09:41 |
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To Make the First Decision |
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Return for Revision |
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2021-05-05 14:41 |
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Revised |
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2021-05-14 20:12 |
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Second Decision |
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2021-10-18 06:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-10-18 09:26 |
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Articles in Press |
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2021-10-18 09:26 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-11-22 05:01 |
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Publish the Manuscript Online |
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2021-11-25 08:31 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Review |
| Article Title |
Regulation of the mesenchymal stem cell fate by interleukin-17: Implications in osteogenic differentiation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jelena Krstić, Slavko Mojsilović, Sonja S Mojsilović and Juan F Santibanez |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministry of Education, Science and Technological Development of Serbia |
451-03-9/2021-14/200015 |
| Oesterreichische Nationalbank (Austrian Central Bank, Anniversary Fund |
18517 |
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| Corresponding Author |
Juan F Santibanez, PhD, Professor, Research Scientist, Group for Molecular Oncology, Institute for Medical Research, National Institute of Republic of Serbia, University of Belgrade, Dr. Subotića 4, Belgrade 11000, Serbia. jfsantibanez@imi.bg.ac.rs |
| Key Words |
Interleukin-17; Mesenchymal stem cells; Osteoblast; Bone; Osteogenesis; Inflammation |
| Core Tip |
The immune system closely interacts with the bone system in health and disease. Inflammation plays a strategic role in bone homeostasis and turnover. A proinflammatory cytokine interleukin-17 is produced in high amounts after bone damage and can influence mesenchymal stem cells’ fate toward early osteoprogenitor cells, either as a pro-osteogenic or an anti-osteogenic factor. Although these divergent IL-17 roles in bone formation are still not well understood, different conditions of the local microenvironment, the extent of inflammation, and the specific nature and stage of osteoprogenitor cells can influence the response to this cytokine, affecting the final cell differentiation outcome. |
| Publish Date |
2021-11-25 08:31 |
| Citation |
Krstić J, Mojsilović S, Mojsilović SS, Santibanez JF. Regulation of the mesenchymal stem cell fate by interleukin-17: Implications in osteogenic differentiation. World J Stem Cells 2021; 13(11): 1696-1713 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i11/1696.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i11.1696 |
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