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Articles Published Processes
9/2/2014 10:31:00 AM | Browse: 1278 | Download: 997
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Received |
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2013-10-22 16:08 |
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Peer-Review Started |
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2013-10-23 16:29 |
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To Make the First Decision |
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2013-12-04 08:34 |
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Return for Revision |
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2013-12-04 17:02 |
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Revised |
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2013-12-14 21:15 |
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Second Decision |
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2014-01-20 17:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-01-20 18:06 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-02-24 10:18 |
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Publish the Manuscript Online |
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2014-03-06 14:13 |
| Category |
Oncology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Pancreatic cancer stroma: understanding biology leads to new therapeutic strategies
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Agnieszka Anna Rucki and Lei Zheng |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| NIH |
R01 CA169702-01A1 (to Zheng L) |
| NIH |
K23 CA148964-01 (to Zheng L) |
| Johns Hopkins School of Medicine Clinical Scientist Award |
to Zheng L |
| Viragh Foundation and the Skip Viragh Pancreatic Cancer Center at Johns Hopkins |
to Zheng L |
| National Pancreas Foundation |
to Zheng L |
| Lefkofsky Family Foundation |
to Zheng L |
| NCI SPORE in Gastrointestinal Cancers |
P50 CA062924 (to Zheng L) |
| Lustgarten Foundation |
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| Sol Goldman Pancreatic Cancer Center |
to Zheng L |
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| Corresponding Author |
Lei Zheng, MD, PhD, Department of Oncology, The Sidney Kimmel Cancer Center, the Skip Viragh Clinical Pancreatic Cancer Center, and the Sol Goldman Pancreatic Cancer Center, Johns Hopkins University, 1650 Orleans Street, CRB1 Room 488, Baltimore, MD 21287, United States. lzheng6@jhmi.edu |
| Key Words |
Pancreatic ductal adenocarcinoma; Stroma; Tumor microenvironment; Pancreatic stellate cells; Cancer associated fibroblast; Sonic hedgehog; Hepatic growth factor; Fibroblast activation protein |
| Core Tip |
This is a comprehensive review and an update on recent progresses in understanding the role of tumor microenvironment in the growth, invasion and metastasis of pancreatic cancer. The role of tumor microenvironment in anti-tumor immune response and treatment of pancreatic cancer is also reviewed. How our knowledge in tumor microenvironment is translated into the development of pancreatic cancer therapy is discussed.
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| Publish Date |
2014-03-06 14:13 |
| Citation |
Rucki AA, Zheng L. Pancreatic cancer stroma: Understanding biology leads to new therapeutic strategies. World J Gastroenterol 2014; 20(9): 2237-2246 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i9/2237.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i9.2237 |
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