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9/2/2014 10:31:00 AM | Browse: 503 | Download: 320
Publication Name World Journal of Gastroenterology
Manuscript ID 6521
Country/Territory United States
Received
2013-10-22 16:08
Peer-Review Started
2013-10-23 16:29
To Make the First Decision
2013-12-04 08:34
Return for Revision
2013-12-04 17:02
Revised
2013-12-14 21:15
Second Decision
2014-01-20 17:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-01-20 18:06
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-02-24 10:18
Publish the Manuscript Online
2014-03-06 14:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Topic Highlights
Article Title Pancreatic cancer stroma: understanding biology leads to new therapeutic strategies
Manuscript Source Invited Manuscript
All Author List Agnieszka Anna Rucki and Lei Zheng
Funding Agency and Grant Number
Funding Agency Grant Number
NIH R01 CA169702-01A1 (to Zheng L)
NIH K23 CA148964-01 (to Zheng L)
Johns Hopkins School of Medicine Clinical Scientist Award to Zheng L
Viragh Foundation and the Skip Viragh Pancreatic Cancer Center at Johns Hopkins to Zheng L
National Pancreas Foundation to Zheng L
Lefkofsky Family Foundation to Zheng L
NCI SPORE in Gastrointestinal Cancers P50 CA062924 (to Zheng L)
Lustgarten Foundation
Sol Goldman Pancreatic Cancer Center to Zheng L
Corresponding author Lei Zheng, MD, PhD, Department of Oncology, The Sidney Kimmel Cancer Center, the Skip Viragh Clinical Pancreatic Cancer Center, and the Sol Goldman Pancreatic Cancer Center, Johns Hopkins University, 1650 Orleans Street, CRB1 Room 488, Baltimore, MD 21287, United States. lzheng6@jhmi.edu
Key Words Pancreatic ductal adenocarcinoma; Stroma; Tumor microenvironment; Pancreatic stellate cells; Cancer associated fibroblast; Sonic hedgehog; Hepatic growth factor; Fibroblast activation protein
Core Tip This is a comprehensive review and an update on recent progresses in understanding the role of tumor microenvironment in the growth, invasion and metastasis of pancreatic cancer. The role of tumor microenvironment in anti-tumor immune response and treatment of pancreatic cancer is also reviewed. How our knowledge in tumor microenvironment is translated into the development of pancreatic cancer therapy is discussed.
Publish Date 2014-03-06 14:13
Citation Rucki AA, Zheng L. Pancreatic cancer stroma: Understanding biology leads to new therapeutic strategies. World J Gastroenterol 2014; 20(9): 2237-2246
Url http://www.wjgnet.com/1007-9327/full/v20/i9/2237.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i9.2237
Full Article (PDF) WJG-20-2237.pdf
Full Article (Word) WJG-20-2237.doc
Manuscript File 6521-Review.docx
Answering Reviewers 6521-Answering reviewers.pdf
Copyright License Agreement 6521-Copyright assignment.pdf
Peer-review Report 6521-Peer review(s).pdf
Scientific Editor Work List 6521-Scientific editor work list.doc