Publication Name	World Journal of Gastroenterology
Manuscript ID	65338
Country	United Kingdom

Received	2021-03-04 13:15
Peer-Review Started	2021-03-04 13:23
To Make the First Decision
Return for Revision	2021-06-03 23:20
Revised	2021-06-30 06:01
Second Decision	2021-10-29 09:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-10-31 18:12
Articles in Press	2021-10-31 18:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-11-16 14:51
Publish the Manuscript Online	2021-11-19 11:15

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Minimum sample size estimates for trials in inflammatory bowel disease: A systematic review of a support resource
Manuscript Source	Invited Manuscript
All Author List	Morris Gordon, Svetlana Lakunina, Vasiliki Sinopoulou and Anthony Akobeng
ORCID	Author(s) ORCID Number Morris Gordon http://orcid.org/0000-0002-1216-5158 Svetlana Lakunina http://orcid.org/0000-0002-3180-6336 Vasiliki Sinopoulou http://orcid.org/0000-0002-2831-9406 Anthony Akobeng http://orcid.org/0000-0001-5418-3728
Funding Agency and Grant Number
Corresponding Author	Morris Gordon, MBChB, PhD, Professor, Biomedical Evidence Synthesis and Translation to Practice Unit, School of Medicine, HA340, Harrington Building, 135A Adelphi St, Preston PR1 7BH, United Kingdom. mgordon@uclan.ac.uk
Key Words	Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Gastroenterology; Statistics; Sample size
Core Tip	This work has identified a large variation in the estimated minimal clinically important difference (MCID) between study groups in inflammatory bowel disease trials in the literature, with no standard to support study designers or reviewers. We have provided a resource to support sample size estimation based on observed MICD in the literature over the last 25 years.
Publish Date	2021-11-19 11:15
Citation	Gordon M, Lakunina S, Sinopoulou V, Akobeng A. Minimum sample size estimates for trials in inflammatory bowel disease: A systematic review of a support resource. World J Gastroenterol 2021; 27(43): 7572-7581
URL	https://www.wjgnet.com/1007-9327/full/v27/i43/7572.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i43.7572

Full Article (PDF)	WJG-27-7572.pdf
Full Article (Word)	WJG-27-7572.docx
Manuscript File	65338_Auto_Edited.docx
Answering Reviewers	65338-Answering reviewers.pdf
Audio Core Tip	65338-Audio core tip.m4a
Biostatistics Review Certificate	65338-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	65338-Conflict-of-interest statement.pdf
Copyright License Agreement	65338-Copyright license agreement.pdf
Supplementary Material	65338-Supplementary material.pdf
Peer-review Report	65338-Peer-review(s).pdf
Scientific Misconduct Check	65338-Bing-Liu M-1.png
Scientific Misconduct Check	65338-Bing-Fan JR-2.png
Scientific Editor Work List	65338-Scientific editor work list.pdf