Publication Name	World Journal of Anesthesiology
Manuscript ID	6549
Country	Mexico

Received	2013-10-23 14:30
Peer-Review Started	2013-10-24 11:22
To Make the First Decision	2014-01-08 14:46
Return for Revision	2014-01-09 12:22
Revised
Second Decision	2014-04-29 08:25
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-29 08:39
Articles in Press	2014-05-23 08:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-18 21:36
Publish the Manuscript Online	2014-08-20 21:05

ISSN	2218-6182 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Anesthesiology
Manuscript Type	Frontier
Article Title	Immunomodulatory effects of dexmedetomidine: from bench to clinic
Manuscript Source	Invited Manuscript
All Author List	Carlos Rodrigo Camara-Lemarroy, Erick Joel Rendon-Ramirez and Beatriz Elena Ibarra-Yruegas
Funding Agency and Grant Number
Corresponding Author	Carlos Rodrigo Camara-Lemarroy, MD, Internal Medicine Department, University Hospital “Dr. José E. González”, Autonomous University of Nuevo Leon, Madero y Gonzalitos S/N, 64460 Monterrey, Mexico. crcamara83@hotmail.com
Key Words	Dexmedetomidine; Immunomodulation; Inflammation; Sepsis; Anesthesia
Core Tip	Dexmedetomdine is a sedative-analgesic agent widely used in intensive-care units. It has favorable hemodynamic, opioid-sparing and delirium-preventive properties. In addition, experimental evidence suggests it has immunomodulating effects, including reduction of inflammatory cytokine release and oxidative stress. Future studies should address the question of whether these properties can be used to alter the course of devastating conditions such as ischemia-reperfusion injury and sepsis.
Publish Date	2014-08-20 21:05
Citation	Camara-Lemarroy CR, Rendon-Ramirez EJ, Ibarra-Yruegas BE. immunomodulatory effects of dexmedetomidine: from bench to clinic.World J Anesthesiol 2014; 3(2): 137-145
URL	http://www.wjgnet.com/2218-6182/full/v3/i2/137.htm
DOI	http://dx.doi.org/10.5313/wja.v3.i2.137

Manuscript File	6549-Review.doc
Answering Reviewers	6549-Anaswering reviewers.pdf
Copyright License Agreement	6549-Copyright assignment.pdf
Peer-review Report	6549-Peer review(s).pdf
Scientific Editor Work List	6549-Scientific editor work list.doc