| Category |
Oncology |
| Manuscript Type |
Autobiography |
| Article Title |
Evaluation of routine biopsies in endoscopic screening for esophagogastric junction cancer
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Xin Niu, Wen-Qiang Wei, Chang-Qing Hao, Guo-Hui Song, Jun Li, Zhao-Lai Hua, Yong-Wei Li, Jun Chang, Xin-Zheng Wang, De-Li Zhao, Guo-Qing Wang, Evelyn Hsieh and You-Lin Qiao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81241091 |
|
| Corresponding Author |
Wen-Qiang Wei, MD, PhD, Department of Cancer Epidemiology, Cancer Institute/Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, 17 South Panjiayuan Lane, PO Box 2258, Beijing 100021,
China. weiwq@cicams.ac.cn |
| Key Words |
Esophagogastric junction cancer; High incidence spot; Screening; Endoscopy; Biopsy |
| Core Tip |
Our findings offer population-level evidence for the high incidence spot of esophagogastric junction (EGJ) cancer. It is also the first study to evaluate whether the findings at the high incidence spot could be used in endoscopic screening in high-risk populations to increase the detection rate. We found that visible mucosal abnormalities of the EGJ at endoscopy were strongly associated with pathologic diagnoses of high-grade intraepithelial neoplasia or higher grade lesions. When no abnormalities were detected, routine biopsies from normal-appearing mucosa at the high incidence spot in endoscopic screening were unjustified in high-risk populations. |
| Publish Date |
2014-05-07 10:10 |
| Citation |
Niu X, Wei WQ, Hao CQ, Song GH, Li J, Hua ZL, Li YW, Chang J, Wang XZ, Zhao DL, Wang GQ, Hsieh E, Qiao YL. Evaluation of routine biopsies in endoscopic screening for esophagogastric junction cancer. World J Gastroenterol 2014; 20(17): 5074-5081 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i17/5074.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i17.5074 |
