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Articles Published Processes
12/24/2021 9:48:20 AM | Browse: 493 | Download: 1064
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Received |
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2021-03-19 11:45 |
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Peer-Review Started |
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2021-03-19 11:50 |
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To Make the First Decision |
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Return for Revision |
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2021-05-01 03:45 |
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Revised |
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2021-05-08 11:56 |
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Second Decision |
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2021-12-08 07:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-12-10 02:48 |
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Articles in Press |
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2021-12-10 02:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-12-17 04:01 |
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Publish the Manuscript Online |
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2021-12-24 09:48 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Frontier |
| Article Title |
Palmitoylation in Crohn’s disease: Current status and future directions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Wei-Xin Cheng, Yue Ren, Miao-Miao Lu, Ling-Ling Xu, Jian-Guo Gao, Dong Chen, Farhin Shaheed Kalyani, Zi-Yan Lv, Chun-Xiao Chen, Feng Ji, He-Ning Lin and Xi Jin |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xi Jin, PhD, Professor, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. jxfl007@zju.edu.cn |
| Key Words |
S-palmitoylation; Crohn’s disease; STING; Pathogenesis; Signaling pathway; Drug therapy |
| Core Tip |
S-palmitoylation is one of the most common post-translational modifications in nature; however, its importance has been overlooked for decades. Crohn’s disease (CD) is an autoimmune disease characterized by chronic inflammation of the entire gastrointestinal tract, whose underlying mechanisms of action remain poorly understood. Recent studies have revealed a key role of S-palmitoylation in CD; therefore, there is a need to elucidate the relationship between CD and S-palmitoylation. This review summarizes the basic facts of S-palmitoylation and its potential effect on CD to provide novel insights into the pathogenesis and treatment of CD. |
| Publish Date |
2021-12-24 09:48 |
| Citation |
Cheng WX, Ren Y, Lu MM, Xu LL, Gao JG, Chen D, Kalyani FS, Lv ZY, Chen CX, Ji F, Lin HN, Jin X. Palmitoylation in Crohn’s disease: Current status and future directions. World J Gastroenterol 2021; 27(48): 8201-8215 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i48/8201.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i48.8201 |
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