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12/24/2021 9:48:20 AM | Browse: 325 | Download: 687
Publication Name World Journal of Gastroenterology
Manuscript ID 65701
Country China
Received
2021-03-19 11:45
Peer-Review Started
2021-03-19 11:50
To Make the First Decision
Return for Revision
2021-05-01 03:45
Revised
2021-05-08 11:56
Second Decision
2021-12-08 07:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-12-10 02:48
Articles in Press
2021-12-10 02:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-12-17 04:01
Publish the Manuscript Online
2021-12-24 09:48
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Frontier
Article Title Palmitoylation in Crohn’s disease: Current status and future directions
Manuscript Source Invited Manuscript
All Author List Wei-Xin Cheng, Yue Ren, Miao-Miao Lu, Ling-Ling Xu, Jian-Guo Gao, Dong Chen, Farhin Shaheed Kalyani, Zi-Yan Lv, Chun-Xiao Chen, Feng Ji, He-Ning Lin and Xi Jin
ORCID
Author(s) ORCID Number
Wei-Xin Cheng http://orcid.org/0000-0003-1764-0779
Yue Ren http://orcid.org/0000-0001-9071-2738
Miao-Miao Lu http://orcid.org/0000-0002-9328-8239
Ling-Ling Xu http://orcid.org/0000-0002-6668-3057
Jian-Guo Gao http://orcid.org/0000-0002-9414-5395
Dong Chen http://orcid.org/0000-0003-3892-9248
Farhin Shaheed Kalyani http://orcid.org/0000-0001-8276-8125
Zi-Yan Lv http://orcid.org/0000-0003-3987-1009
Chun-Xiao Chen http://orcid.org/0000-0001-7536-1191
Feng Ji http://orcid.org/0000-0003-4252-8850
He-Ning Lin http://orcid.org/0000-0002-0255-2701
Xi Jin http://orcid.org/0000-0001-9985-3035
Funding Agency and Grant Number
Corresponding Author Xi Jin, PhD, Professor, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. jxfl007@zju.edu.cn
Key Words S-palmitoylation; Crohn’s disease; STING; Pathogenesis; Signaling pathway; Drug therapy
Core Tip S-palmitoylation is one of the most common post-translational modifications in nature; however, its importance has been overlooked for decades. Crohn’s disease (CD) is an autoimmune disease characterized by chronic inflammation of the entire gastrointestinal tract, whose underlying mechanisms of action remain poorly understood. Recent studies have revealed a key role of S-palmitoylation in CD; therefore, there is a need to elucidate the relationship between CD and S-palmitoylation. This review summarizes the basic facts of S-palmitoylation and its potential effect on CD to provide novel insights into the pathogenesis and treatment of CD.
Publish Date 2021-12-24 09:48
Citation Cheng WX, Ren Y, Lu MM, Xu LL, Gao JG, Chen D, Kalyani FS, Lv ZY, Chen CX, Ji F, Lin HN, Jin X. Palmitoylation in Crohn’s disease: Current status and future directions. World J Gastroenterol 2021; 27(48): 8201-8215
URL https://www.wjgnet.com/1007-9327/full/v27/i48/8201.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i48.8201
Full Article (PDF) WJG-27-8201.pdf
Full Article (Word) WJG-27-8201.docx
Manuscript File 65701_Auto_Edited-YJM.docx
Answering Reviewers 65701-Answering reviewers.pdf
Audio Core Tip 65701-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 65701-Conflict-of-interest statement.pdf
Copyright License Agreement 65701-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 65701-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 65701-Language certificate.pdf
Peer-review Report 65701-Peer-review(s).pdf
Scientific Editor Work List 65701-Scientific editor work list.pdf