Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	65854
Country	United States

Received	2021-03-16 19:18
Peer-Review Started	2021-03-16 19:30
To Make the First Decision
Return for Revision	2021-05-03 05:02
Revised	2021-05-17 02:56
Second Decision	2021-08-06 03:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-08-06 08:00
Articles in Press	2021-08-06 08:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-09-03 14:35
Publish the Manuscript Online	2021-09-10 12:09

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Neoadjuvant chemotherapy for colorectal liver metastases: A contemporary review of the literature
Manuscript Source	Invited Manuscript
All Author List	Marissa Guo, Ning Jin, Timothy Pawlik and Jordan M Cloyd
ORCID	Author(s) ORCID Number Marissa Guo http://orcid.org/0000-0002-6200-6577 Ning Jin http://orcid.org/0000-0002-6689-4671 Timothy Pawlik http://orcid.org/0000-0002-7994-9870 Jordan M Cloyd http://orcid.org/0000-0002-2373-8433
Funding Agency and Grant Number
Corresponding Author	Jordan M Cloyd, MD, Assistant Professor, Department of Surgery, Division of Surgical Oncology, The Ohio State University Medical Center, N907 Doan Hall, 410 W 10th Ave, Columbus, OH 43210, United States. jordan.cloyd@osumc.edu
Key Words	Colorectal liver metastases; Neoadjuvant chemotherapy; Hepatic resection; Conversion therapy; Chemotherapy-associated liver injury; Disappearing liver metastases; Future liver remnant; Immunotherapy
Core Tip	Colorectal carcinoma is one of the leading causes of cancer-related deaths worldwide. Neoadjuvant chemotherapy is an important treatment strategy for patients with colorectal liver metastases that can downstage tumors and facilitate hepatic resection. Although its use in patients with initially resectable disease is controversial, it is currently recommended for those with unresectable to borderline resectable metastases.
Publish Date	2021-09-10 12:09
Citation	Guo M, Jin N, Pawlik T, Cloyd JM. Neoadjuvant chemotherapy for colorectal liver metastases: A contemporary review of the literature. World J Gastrointest Oncol 2021; 13(9): 1043-1061
URL	https://www.wjgnet.com/1948-5204/full/v13/i9/1043.htm
DOI	https://dx.doi.org/10.4251/wjgo.v13.i9.1043

Full Article (PDF)	WJGO-13-1043.pdf
Full Article (Word)	WJGO-13-1043.docx
Manuscript File	65854_Auto_Edited-JPY.docx
Answering Reviewers	65854-Answering reviewers.pdf
Audio Core Tip	65854-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	65854-Conflict-of-interest statement.pdf
Copyright License Agreement	65854-Copyright license agreement.pdf
Peer-review Report	65854-Peer-review(s).pdf
Scientific Misconduct Check	65854-Scientific misconduct check.pdf
Scientific Editor Work List	65854-Scientific editor work list.pdf