Publication Name	World Journal of Gastroenterology
Manuscript ID	65859
Country	Romania

Received	2021-03-18 18:43
Peer-Review Started	2021-03-17 16:14
To Make the First Decision
Return for Revision	2021-08-09 18:15
Revised	2021-08-13 21:01
Second Decision	2021-11-02 03:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-11-03 01:14
Articles in Press	2021-11-03 01:14
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-10-22 06:05
Typeset the Manuscript	2021-11-16 15:06
Publish the Manuscript Online	2021-11-19 11:15

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Overview of the microbiota in the gut-liver axis in viral B and C hepatitis
Manuscript Source	Invited Manuscript
All Author List	Maria Adriana Neag, Andrei Otto Mitre, Adrian Catinean and Anca Dana Buzoianu
ORCID	Author(s) ORCID Number Maria Adriana Neag http://orcid.org/0000-0002-3904-2852 Andrei Otto Mitre http://orcid.org/0000-0002-1121-4042 Adrian Catinean http://orcid.org/0000-0002-6327-6608 Anca Dana Buzoianu http://orcid.org/0000-0002-3511-2788
Funding Agency and Grant Number
Corresponding Author	Andrei Otto Mitre, N/A, N/A, N/A, Faculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy of Cluj-Napoca, 8. Babes Street, Cluj-Napoca 400012, Romania. andrei.otto.mitre@elearn.umfcluj.ro
Key Words	Viral B hepatitis; Viral C hepatitis; Gut-liver axis; Immunomodulation; Lipopolysaccharides; Short-chain fatty acids
Core Tip	We have provided an overview of the mechanisms involved in the immunomodulation of the gut-liver axis. We highlight the mechanisms by which hepatitis B virus and hepatitis C virus infections influence the microbiota and how in turn these changes affect the liver pathology. We have also looked at the current treatment options and their influence on the intestinal microflora.
Publish Date	2021-11-19 11:15
Citation	Neag MA, Mitre AO, Catinean A, Buzoianu AD. Overview of the microbiota in the gut-liver axis in viral B and C hepatitis. World J Gastroenterol 2021; 27(43): 7446-7461
URL	https://www.wjgnet.com/1007-9327/full/v27/i43/7446.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i43.7446

Full Article (PDF)	WJG-27-7446.pdf
Full Article (Word)	WJG-27-7446.docx
Manuscript File	65859_Auto_edited-CCG-Filipodia.docx
Answering Reviewers	65859-Answering reviewers.pdf
Audio Core Tip	65859-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	65859-Conflict-of-interest statement.pdf
Copyright License Agreement	65859-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	65859-Language certificate.pdf
Peer-review Report	65859-Peer-review(s).pdf
Scientific Editor Work List	65859-Scientific editor work list.pdf
CrossCheck Report	65859-CrossCheck report.pdf