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Articles Published Processes
8/10/2021 6:48:42 AM | Browse: 415 | Download: 1086
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Received |
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2021-03-31 12:08 |
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Peer-Review Started |
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2021-03-31 12:17 |
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To Make the First Decision |
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Return for Revision |
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2021-05-28 01:04 |
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Revised |
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2021-06-07 11:44 |
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Second Decision |
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2021-07-12 03:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-13 06:29 |
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Articles in Press |
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2021-07-13 06:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-21 06:50 |
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Typeset the Manuscript |
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2021-08-06 10:34 |
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Publish the Manuscript Online |
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2021-08-10 06:48 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Association of gene and protein expression and genetic polymorphism of CC chemokine ligand 4 in colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Levar Shamoun, Kalle Landerholm, Amanda Balboa Ramilo, Roland E Andersson, Jan Dimberg and Dick Wågsäter |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Medical Research Council of Southeast Sweden (FORSS) and Division of Medical Diagnostics (Futurum), Region Jönköping County, Sweden |
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| Corresponding Author |
Dick Wågsäter, PhD, Professor, Department of Medical Cell Biology, Uppsala University, Husargatan 3, Uppsala 75237, Sweden. dick.wagsater@mcb.uu.se |
| Key Words |
CC chemokine ligand 4; Gene polymorphism; Gene and protein expression; Chemokine; Survival rate; Colorectal cancer |
| Core Tip |
Our data suggest that the CC chemokine ligand (CCL) 4 rs10491121 polymorphism is associated with colorectal cancer (CRC), particularly mucinous CRC and CRC in the right colon. Moreover, we observed that CCL4 protein expression was upregulated in CRC tissues compared with in normal tissues, was correlated with disease stage and that low expression was related to a 30% lower cancer-specific survival rate. |
| Publish Date |
2021-08-10 06:48 |
| Citation |
Shamoun L, Landerholm K, Balboa Ramilo A, Andersson RE, Dimberg J, Wågsäter D. Association of gene and protein expression and genetic polymorphism of CC chemokine ligand 4 in colorectal cancer. World J Gastroenterol 2021; 27(30): 5076-5087 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i30/5076.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i30.5076 |
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