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Articles Published Processes
9/15/2014 6:06:00 PM | Browse: 1276 | Download: 1174
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Received |
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2013-10-25 15:14 |
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Peer-Review Started |
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2013-10-25 19:51 |
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To Make the First Decision |
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2013-11-12 14:30 |
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Return for Revision |
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2013-11-12 17:05 |
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Revised |
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2013-12-05 09:21 |
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Second Decision |
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2014-01-06 20:14 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-01-06 20:30 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-01-26 16:49 |
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Publish the Manuscript Online |
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2014-02-15 15:06 |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Topic Highlights |
Article Title |
Dendritic cells derived from pluripotent stem cells: potential of large scale production
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Manuscript Source |
Invited Manuscript |
All Author List |
Yan Li, Meimei Liu and Shang-Tian Yang |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Research of Foundation of the South Korea |
2012M3A9C7050101 |
National Research of Foundation of the South Korea |
2011-0030028 |
National Research of Foundation of the South Korea |
2006-2004112 |
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Corresponding Author |
Kwang-Hee Bae, PhD, Director, Research Center for Integrated Cellulomics, KRIBB, Daejeon 305-806, South Korea. khbae@kribb.re.kr |
Key Words |
Pluripotent stem cells; dendritic cells; bioreactor; hematopoietic differentiation; large scale production |
Core Tip |
Human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) are promising sources for hematopoietic cells. This review summarizes recent advances in differentiating hESCs and hiPSCs to dendritic cells (DCs), which are unique immune cells in the hematopoietic system and can be loaded with tumor specific antigen and used as vaccine for cancer immunotherapy. While autologous DCs from peripheral blood are limited in number, human PSC (hPSC)-derived DCs provide a novel alternative cell source for clinical application. Different strategies and effects of shear stress on large-scale production of hPSC-derived DCs in bioreactors are also discussed. |
Publish Date |
2014-02-15 15:06 |
Citation |
Park A, Kim WK, Bae KH. Distinction of white, beige and brown adipocytes derived from mesenchymal stem cells. World J Stem Cells 2014; 6(1): 33-42 |
URL |
http://www.wjgnet.com/1948-0210/full/v6/i1/33.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v6.i1.33 |
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