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Articles Published Processes
1/20/2022 10:47:59 AM | Browse: 381 | Download: 652
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Received |
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2021-03-24 16:45 |
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Peer-Review Started |
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2021-03-24 16:47 |
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To Make the First Decision |
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Return for Revision |
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2021-06-05 01:43 |
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Revised |
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2021-06-21 20:56 |
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Second Decision |
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2021-12-31 03:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-12-31 22:31 |
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Articles in Press |
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2021-12-31 22:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-01-06 08:29 |
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Publish the Manuscript Online |
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2022-01-20 10:47 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Stem cell therapy applied for digestive anastomosis: Current state and future perspectives
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jacobo Trébol, Tihomir Georgiev-Hristov, Isabel Pascual-Miguelañez, Hector Guadalajara, Mariano García-Arranz and Damian García-Olmo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jacobo Trébol, MD, PhD, Adjunct Professor, Surgeon, Surgical Oncologist, Servicio de Cirugía General y del Aparato Digestivo, Complejo Asistencial Universitario de Salamanca, Paseo de San Vicente, No. 58-182, Salamanca 37007, Spain. jtrebol@saludcastillayleon.es |
| Key Words |
Surgical anastomosis; Anastomotic leak; Digestive system surgical procedure; Cell transplantation; Cell therapy; Stem cells; Tissue engineering |
| Core Tip |
Digestive anastomoses leakages reflect impaired healing, are frequent and are associated with severe consequences. Despite technical and technological advancements, leakage rates have remained stable in the last decades. Stem cells (SCs) could improve anastomotic healing, as they have in other altered healing conditions. We present a descriptive review of the published literature about digestive anastomoses and sutures and SCs, analyzing the results and discussing their limitations and concerns. Eighteen preclinical studies have confirmed the feasibility and safety and have shown interesting results, however, with some limitations and high heterogenicity. Additional studies and better models are needed prior to human testing. |
| Publish Date |
2022-01-20 10:47 |
| Citation |
Trébol J, Georgiev-Hristov T, Pascual-Miguelañez I, Guadalajara H, García-Arranz M, García-Olmo D. Stem cell therapy applied for digestive anastomosis: Current state and future perspectives. World J Stem Cells 2022; 14(1): 117-141 |
| URL |
https://www.wjgnet.com/1948-0210/full/v14/i1/117.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v14.i1.117 |
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