Publication Name	World Journal of Gastroenterology
Manuscript ID	66346
Country	Russia

Received	2021-03-25 19:40
Peer-Review Started	2021-03-25 19:44
To Make the First Decision
Return for Revision	2021-06-26 04:45
Revised	2021-07-02 13:17
Second Decision	2021-12-16 03:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-12-22 23:33
Articles in Press	2021-12-22 23:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-12-23 02:47
Publish the Manuscript Online	2021-12-24 09:48

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Issues of origin, morphology and clinical significance of tumor microvessels in gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Marina A Senchukova
ORCID	Author(s) ORCID Number Marina A Senchukova http://orcid.org/0000-0001-8371-740X
Funding Agency and Grant Number
Corresponding Author	Marina A Senchukova, MD, PhD, Professor, Department of Oncology, Orenburg State Medical University, Sovetskaya street, Orenburg 460021, Russia. masenchukova@yandex.com
Key Words	Gastric cancer; Angiogenesis; Tumor microvessels; Vascular endothelial growth factor; Hypoxia; Prognosis
Core Tip	In this review, data on the factors associated with the activation of angiogenesis in tumors, the mechanisms of tumor microvessel formation and the features of their morphology, methods for assessing the activity of angiogenesis in a tumor, and their role in the progression of gastric cancer (GC) are discussed. A new classification of tumor microvessels in GC based on their morphology and clinical significance is proposed. Considering the different types of tumor microvessels can have different sensitivities to antiangiogenic therapy, further study of their prognostic and predictive value is undoubtedly relevant.
Publish Date	2021-12-24 09:48
Citation	Senchukova MA. Issues of origin, morphology and clinical significance of tumor microvessels in gastric cancer. World J Gastroenterol 2021; 27(48): 8262-8282
URL	https://www.wjgnet.com/1007-9327/full/v27/i48/8262.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i48.8262

Full Article (PDF)	WJG-27-8262.pdf
Full Article (Word)	WJG-27-8262.docx
Manuscript File	66346_Auto_Edited.docx
Answering Reviewers	66346-Answering reviewers.pdf
Audio Core Tip	66346-Audio core tip.aac
Conflict-of-Interest Disclosure Form	66346-Conflict-of-interest statement.pdf
Copyright License Agreement	66346-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	66346-Language certificate.pdf
Peer-review Report	66346-Peer-review(s).pdf
Scientific Editor Work List	66346-Scientific editor work list.pdf
CrossCheck Report	66346-CrossCheck report.pdf