Publication Name	World Journal of Biological Chemistry
Manuscript ID	66353
Country	Japan

Received	2021-03-26 02:43
Peer-Review Started	2021-03-26 02:47
To Make the First Decision
Return for Revision	2021-05-06 00:20
Revised	2021-05-21 07:40
Second Decision	2021-11-26 03:32
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-11-28 08:13
Articles in Press	2021-11-28 08:13
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-11-22 00:07
Typeset the Manuscript	2021-11-29 02:29
Publish the Manuscript Online	2021-12-14 05:28

ISSN	1949-8454 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Neurosciences
Manuscript Type	Minireviews
Article Title	Neuroprotection by dipeptidyl-peptidase-4 inhibitors and glucagon-like peptide-1 analogs via the modulation of AKT-signaling pathway in Alzheimer’s disease
Manuscript Source	Invited Manuscript
All Author List	Yuka Ikeda, Nozomi Nagase, Ai Tsuji, Yasuko Kitagishi and Satoru Matsuda
ORCID	Author(s) ORCID Number Yuka Ikeda http://orcid.org/0000-0003-4805-1758 Nozomi Nagase http://orcid.org/0000-0003-3665-5714 Ai Tsuji http://orcid.org/0000-0003-1619-7592 Yasuko Kitagishi http://orcid.org/0000-0002-6906-7444 Satoru Matsuda http://orcid.org/0000-0003-4274-5345
Funding Agency and Grant Number
Corresponding Author	Satoru Matsuda, MD, PhD, Professor, Food Science and Nutrition, Nara Women's University, Kita-Uoya Nishimachi, Nara 630-8506, Japan. smatsuda@cc.nara-wu.ac.jp
Key Words	Alzheimer’s disease; Cognitive disorder; Dementia; Glucagon-like peptide-1; Dipeptidyl peptidase-4; Mammalian/mechanistic target of rapamycin
Core Tip	Disorders of mammalian/mechanistic target of rapamycin (mTOR) signaling pathways are related to Alzheimer’s disease (AD). Although further studies for mTOR, glucagon-like peptide-1, and dipeptidyl-peptidase-4 signaling are needed, they seem to be a promising approach for innovative AD-treatments.
Publish Date	2021-12-14 05:28
Citation	Ikeda Y, Nagase N, Tsuji A, Kitagishi Y, Matsuda S. Neuroprotection by dipeptidyl-peptidase-4 inhibitors and glucagon-like peptide-1 analogs via the modulation of AKT-signaling pathway in Alzheimer’s disease. World J Biol Chem 2021; 12(6) 104-113
URL	https://www.wjgnet.com/1949-8454/full/v12/i6/104.htm
DOI	https://dx.doi.org/10.4331/wjbc.v12.i6.104

Full Article (PDF)	WJBC-12-104.pdf
Full Article (Word)	WJBC-12-104.docx
Manuscript File	66353_Auto_Edited-CKL-Filipodia.docx
Answering Reviewers	66353-Answering reviewers.pdf
Audio Core Tip	66353-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	66353-Conflict-of-interest statement.pdf
Copyright License Agreement	66353-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	66353-Language certificate.pdf
Peer-review Report	66353-Peer-review(s).pdf
Scientific Misconduct Check	66353-Bing-Chang KL-2.png
Scientific Misconduct Check	66353-Bing-Ma YJ-1.jpg
Scientific Editor Work List	66353-Scientific editor work list.pdf
CrossCheck Report	66353-CrossCheck report.pdf