Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	66395
Country	Brazil

Received	2021-03-26 21:14
Peer-Review Started	2021-03-26 21:20
To Make the First Decision
Return for Revision	2021-07-27 02:38
Revised	2021-08-08 23:01
Second Decision	2021-10-29 09:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-10-31 18:21
Articles in Press	2021-10-31 18:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-11-05 05:46
Publish the Manuscript Online	2021-11-09 07:27

ISSN	2219-2808 (online)
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Category	Pediatrics
Manuscript Type	Minireviews
Article Title	Beyond kidney stones: Why pediatricians should worry about hypercalciuria
Manuscript Source	Invited Manuscript
All Author List	Maria Goretti Moreira Guimarães Penido and Marcelo de Sousa Tavares
ORCID	Author(s) ORCID Number Maria Goretti Moreira Guimarães Penido http://orcid.org/0000-0002-1534-3861 Marcelo de Sousa Tavares http://orcid.org/0000-0002-9766-9354
Funding Agency and Grant Number
Corresponding Author	Maria Goretti Moreira Guimarães Penido, MD, PhD, Associate Professor, Chief Doctor, Professor, Pediatric Nephrology Unit, Nephrology Center, Santa Casa de Belo Horizonte Hospital, Rua Piauí 420 CEP 30150320, Minas Gerais, Brazil, Belo Horizonte 30150320, Minas Gerais, Brazil. mariagorettipenido@yahoo.com.br
Key Words	Children; Adolescents; Hypercalciuria; Bone mineral density; Kidney stone
Core Tip	The incidence of pediatric urolithiasis is increasing, and hypercalciuria is its leading metabolic risk factor. The reduction in bone mass has already been described in hypercalciuric children, and the precise mechanisms of bone loss or failure to achieve adequate bone mass remain unknown. The peak bone mass is achieved by late adolescence, peaking at the end of the second decade of life. This accumulation should occur without interference. The bone mass acquired during childhood and adolescence is the major determinant of adult bone health. Pediatricians should have the knowledge and ability to diagnose and manage pediatric patients with idiopathic hypercalciuria.
Publish Date	2021-11-09 07:27
Citation	Penido MGMG, Tavares MS. Beyond kidney stones: Why pediatricians should worry about hypercalciuria. World J Clin Pediatr 2021; 10(6): 137-150
URL	https://www.wjgnet.com/2219-2808/full/v10/i6/137.htm
DOI	https://dx.doi.org/10.5409/wjcp.v10.i6.137

Full Article (PDF)	WJCP-10-137.pdf
Full Article (Word)	WJCP-10-137.docx
Manuscript File	66395_Auto_Edited.docx
Answering Reviewers	66395-Answering reviewers.pdf
Audio Core Tip	66395-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	66395-Conflict-of-interest statement.pdf
Copyright License Agreement	66395-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	66395-Language certificate.pdf
Peer-review Report	66395-Peer-review(s).pdf
Scientific Misconduct Check	66395-Bing-Wang LL-2.png
Scientific Editor Work List	66395-Scientific editor work list.pdf
CrossCheck Report	66395-CrossCheck report.pdf