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Articles Published Processes
10/26/2021 8:04:00 AM | Browse: 435 | Download: 1005
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Received |
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2021-04-19 15:19 |
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Peer-Review Started |
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2021-04-19 15:21 |
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To Make the First Decision |
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Return for Revision |
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2021-08-09 18:34 |
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Revised |
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2021-08-21 15:41 |
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Second Decision |
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2021-09-13 02:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-09-17 00:41 |
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Articles in Press |
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2021-09-17 00:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-10-22 01:52 |
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Publish the Manuscript Online |
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2021-10-26 08:04 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Retrospective Study |
| Article Title |
Outcomes of reduction hepatectomy combined with postoperative multidisciplinary therapy for advanced hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yoh Asahi, Toshiya Kamiyama, Tatsuhiko Kakisaka, Tatsuya Orimo, Shingo Shimada, Akihisa Nagatsu, Takeshi Aiyama, Yuzuru Sakamoto, Hirofumi Kamachi and Akinobu Taketomi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yoh Asahi, MD, PhD, Surgeon, Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Kita-ku, Kita 15, Nishi 7, Sapporo 060-8638, Hokkaido, Japan. yoh-hibana@yk2.so-net.ne.jp |
| Key Words |
Hepatocellular carcinoma; Reduction hepatectomy; Multidisciplinary therapy; Tyrosine kinase inhibitors; Postoperative complete remission |
| Core Tip |
This was a retrospective study examining the outcomes of combination treatment with reduction hepatectomy and multidisciplinary postoperative treatment for advanced hepatocellular carcinoma (HCC). When reduction hepatectomy is performed for unresectable advanced HCC that is not indicated for curative hepatectomy, achieving postoperative complete remission (POCR) via postoperative multidisciplinary therapy is the key to success, with the 5-year overall survival rate and mean survival time for the POCR (+) group being 37.5% and 56.55 mo, respectively. To achieve POCR, reduction hepatectomy should be performed with the aim of reducing the number of tumors in the remnant liver to ≤ 3. Even in cases in which POCR is not achieved, tyrosine kinase inhibitor treatment might improve the prognosis of advanced HCC after reduction hepatectomy. |
| Publish Date |
2021-10-26 08:04 |
| Citation |
Asahi Y, Kamiyama T, Kakisaka T, Orimo T, Shimada S, Nagatsu A, Aiyama T, Sakamoto Y, Kamachi H, Taketomi A. Outcomes of reduction hepatectomy combined with postoperative multidisciplinary therapy for advanced hepatocellular carcinoma. World J Gastrointest Surg 2021; 13(10): 1245-1257 |
| URL |
https://www.wjgnet.com/1948-9366/full/v13/i10/1245.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v13.i10.1245 |
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