Publication Name	World Journal of Gastroenterology
Manuscript ID	6661
Country	United States

Received	2013-10-26 16:44
Peer-Review Started	2013-10-27 12:54
To Make the First Decision	2014-01-09 12:33
Return for Revision	2014-01-11 19:18
Revised	2014-01-30 06:02
Second Decision	2014-04-09 08:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-09 08:57
Articles in Press	2014-05-23 10:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-05 13:57
Publish the Manuscript Online	2014-08-20 18:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Involvement of eicosanoids in the pathogenesis of pancreatic cancer: the roles of cyclooxygenase-2 and 5-lipoxygenase
Manuscript Source	Invited Manuscript
All Author List	Lawrence M Knab, Paul J Grippo and David J Bentrem
Funding Agency and Grant Number
Corresponding Author	David J Bentrem, MD, Department of Surgery, Northwestern University Feinberg School of Medicine, Northwestern University, Suite 650, 676 N St. Clair, Chicago, IL 60611, United States. dbentrem@nmff.org
Key Words	Arachidonic acid; Eicosanoid; Cyclooxygenase-2; 5-lipoxygenase; Pancreatic cancer; Inflammation
Core Tip	This review article highlights the relationship between inflammation and pancreatic cancer, specifically focusing on the enzymes cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). The role of inflammation and tumor progression is a burgeoning area of research. This review delves into the research that has been conducted investigating COX-2 and 5-LOX and their relationship to pancreatic cancer both in vivo and in vitro. We discuss a variety of investigations including basic science, epidemiological, and clinical as they relate to pancreatic inflammation and eicosanoids.
Publish Date	2014-08-20 18:38
Citation	Knab LM, Grippo PJ, Bentrem DJ. involvement of eicosanoids in the pathogenesis of pancreatic cancer: the roles of cyclooxygenase-2 and 5-lipoxygenase. World J Gastroenterol 2014; 20(31): 10729-10739
URL	http://www.wjgnet.com/1007-9327/full/v20/i31/10729.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i31.10729

Full Article (PDF)	WJG-20-10729.pdf
Full Article (Word)	WJG-20-10729.doc
Manuscript File	6661-Review.docx
Answering Reviewers	6661-Answering reviewers.pdf
Copyright License Agreement	6661-Copyright assignment.pdf
Peer-review Report	6661-Peer review(s).pdf
Scientific Editor Work List	6661-Scientific editor work list.doc