Publication Name	World Journal of Hepatology
Manuscript ID	6662
Country	Spain

Received	2013-10-31 18:29
Peer-Review Started	2013-11-14 23:34
First Decision by Editorial Office Director
Return for Revision	2013-12-26 10:31
Revised	2014-01-09 01:05
Publication Fee Transferred
Second Decision by Editor	2014-04-03 10:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-04-03 10:58
Articles in Press
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-08 20:32
Publish the Manuscript Online	2014-05-20 15:05

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Drug-induced autoimmune liver disease: a diagnostic dilemma of an increasingly reported disease
Manuscript Source	Invited Manuscript
All Author List	Agustin Castiella, Eva Zapata, M Isabel Lucena and Raúl J Andrade
Funding Agency and Grant Number
Corresponding Author	Agustin Castiella, PhD, MD, Gastroenterology Service, Mendaro Hospital, Barrio Mendarozabal, 20850 Mendaro, Spain. agustincastiella@yahoo.es
Key Words	Drug-induced liver injury; Autoimmune hepatitis; Drugs; Drug-induced autoimmune hepatitis; Drug-induced autoimmune liver disease
Core Tip	Drug-induced autoimmune liver disease (DIAILD) is a poorly defined and under-reported liver disorder, and, probably, a underestimated liver disease. A small number of drug-induced liver injury (DILI) cases exhibit features typical of autoimmune hepatitis (AIH). To differentiate between true AIH triggered by drugs (DI-AIH) and immune mediated DILI still remains a challenge. Patients diagnosed with DIAILD have frequently had a previous episode of hepatotoxicity. We consider that some basic requirements are needed to be considered before supporting a drug as a trigger of AIH and they should be taken into account by authors, reviewers and editors when cases are published and made available to the scientific community.
Publish Date	2014-05-20 15:05
Citation	Castiella A, Zapata E, Lucena MI, Andrade RJ. drug-induced autoimmune liver disease: a diagnostic dilemma of an increasingly reported disease. World J Hepatol 2014; 6(4): 160-168
URL	http://www.wjgnet.com/1948-5182/full/v6/i4/160.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i4.160

Full Article (PDF)	WJH-6-160.pdf
Full Article (Word)	WJH-6-160.doc
Manuscript File	6662-Review.doc
Answering Reviewers	6662-Answering reviewers.pdf
Copyright License Agreement	6662-Copyright assignment.pdf
Peer-review Report	6662-Peer review(s).pdf
Scientific Editor Work List	6662-Scientific editor work list.doc