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Articles Published Processes
8/25/2021 2:11:51 AM | Browse: 498 | Download: 1030
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Received |
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2021-04-09 05:41 |
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Peer-Review Started |
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2021-04-09 05:44 |
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To Make the First Decision |
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Return for Revision |
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2021-05-27 19:36 |
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Revised |
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2021-06-22 14:37 |
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Second Decision |
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2021-08-10 03:00 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-10 08:17 |
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Articles in Press |
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2021-08-10 08:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-08-23 10:33 |
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Publish the Manuscript Online |
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2021-08-25 02:11 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Prolonged survival in patients with hand-foot skin reaction secondary to cooperative sorafenib treatment
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Masanori Ochi, Toshiro Kamoshida, Masahiro Araki and Tadashi Ikegami |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Masanori Ochi, MD, Doctor, Doctor, Department of Gastroenterology, Hitachi General Hospital, Chome-1-1 Jonancho, Ibaraki 317–0077, Japan. maochi-tei@umin.ac.jp |
Key Words |
Hepatocellular carcinoma; Sorafenib; Pharmacists; Oncologists; Prognosis; Duration of therapy |
Core Tip |
We investigated the effect of cooperation between oncologists and pharmacists (mutual cooperation system) on the prognosis of patients with advanced hepatocellular carcinoma treated with sorafenib and found that cooperation increased medication adherence. Prolonged adherence was correlated with overall survival and time to treatment failure in patients with sorafenib-related hand-foot skin reactions. Our mutual cooperation system could be used to manage patients treated with various multikinase inhibitors and improve overall survival in studies that use sorafenib as the control drug. Future clinical investigations that include measures to improve medication adherence could eliminate the underestimation of medication efficacy that may otherwise occur due to preventable nonadherence. |
Publish Date |
2021-08-25 02:11 |
Citation |
Ochi M, Kamoshida T, Araki M, Ikegami T. Prolonged survival in patients with hand-foot skin reaction secondary to cooperative sorafenib treatment. World J Gastroenterol 2021; 27(32): 5424-5437 |
URL |
https://www.wjgnet.com/1007-9327/full/v27/i32/5424.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v27.i32.5424 |
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