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Articles Published Processes
7/7/2022 10:23:38 AM | Browse: 423 | Download: 786
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Received |
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2021-04-02 21:58 |
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Peer-Review Started |
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2021-04-02 22:01 |
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To Make the First Decision |
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Return for Revision |
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2021-07-31 04:00 |
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Revised |
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2021-08-10 03:27 |
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Second Decision |
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2022-05-07 07:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-05-08 07:21 |
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Articles in Press |
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2022-05-08 07:21 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-06-02 00:52 |
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Publish the Manuscript Online |
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2022-07-07 10:23 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Minireviews |
| Article Title |
Challenges in hyperglycemia management in critically ill patients with COVID-19
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rajesh Kethireddy, Darshan Gandhi, Asim Kichloo and Love Patel |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Darshan Gandhi, MD, Academic Fellow, Doctor, Doctor, Department of Diagnostic Radiology, University of Tennessee Health Science Center, 920 Madison Ave, TN, Memphis 38103, United States. darshan.gandhi@northwestern.edu |
| Key Words |
Hyperglycemia; COVID-19; Critical care; Diabetes; Diabetic ketoacidosis |
| Core Tip |
Hyperglycemia is commonly associated with adverse outcomes especially in patients requiring intensive care unit stay. Data from the corona virus disease 2019 (COVID-19) pandemic indicates that individuals with diabetes appear to be at similar risk for COVID-19 infection to those without diabetes but are more likely to experience increased morbidity and mortality. The proposed hypothesis for hyperglycemia in COVID-19 include insulin resistance, critical illness hyperglycemia (or stress- induced hyperglycemia) secondary to high levels of hormones like cortisol and catecholamines that counteract insulin action, acute cytokine storm and pancreatic cell dysfunction. Diabetic patients are more likely to have severe hyperglycemic complications including diabetic ketoacidosis and hyperosmolar hyperglycemic state. Management of hyperglycemia in COVID-19 is often complicated by use of steroids, prolonged total parenteral or enteral nutrition, frequent acute hyperglycemic events, and restrictions with fluid management due to acute respiratory distress syndrome. While managing hyperglycemia special attention should be paid to mode of insulin delivery, frequency of glucose monitoring based on patient and caregiver safety thereby minimizing exposure and conserving personal protective equipment. In this article we describe the pathophysiology of hyperglycemia, challenges encountered in managing hyperglycemia, and review some potential solutions to address them. |
| Publish Date |
2022-07-07 10:23 |
| Citation |
Kethireddy R, Gandhi D, Kichloo A, Patel L. Challenges in hyperglycemia management in critically ill patients with COVID-19. World J Crit Care Med 2022;11(4): 219-227 |
| URL |
https://www.wjgnet.com/2220-3141/full/v11/i4/219.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v11.i4.219 |
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