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Articles Published Processes
9/23/2021 7:48:08 AM | Browse: 771 | Download: 1167
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Received |
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2021-04-07 17:07 |
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Peer-Review Started |
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2021-04-07 17:10 |
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To Make the First Decision |
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Return for Revision |
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2021-05-27 19:42 |
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Revised |
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2021-06-10 07:51 |
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Second Decision |
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2021-07-12 03:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-13 07:00 |
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Articles in Press |
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2021-07-13 07:00 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-16 17:59 |
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Typeset the Manuscript |
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2021-08-15 13:01 |
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Publish the Manuscript Online |
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2021-09-23 07:48 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Evaluation of biomarkers, genetic mutations, and epigenetic modifications in early diagnosis of pancreatic cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bilal Rah, Manzoor Ahmad Banday, Gh Rasool Bhat, Omar J Shah, Humira Jeelani, Fizalah Kawoosa, Tahira Yousuf and Dil Afroze |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Dil Afroze, PhD, Full Professor, Advanced Centre for Human Genetics, Sher-i-Kashmir Institute of Medical Science, Main Road, Srinagar 190011, Jammu and Kashmir, India. afrozedil@gmail.com |
| Key Words |
Pancreatic cancer; Genetic mutations; Epigenetic modifications; Biomarkers; Risk factors; Diagnostics |
| Core Tip |
This study demonstrates that the collective evaluation of genetic mutations, epigenetic modifications in key genes and elevated levels of serum carbohydrate antigen 19-9, tissue polypeptide specific antigen, carcinoembryonic antigen, and vascular endothelial growth factor-A could be used as predictive biomarkers for diagnostics and prognostics in pancreatic cancer patients of the ethnic Kashmiri population. This could be useful to track the disease status of pancreatic cancer patients who are on a different regimen of chemotherapeutic interventions. To validate these results in the ethnic Kashmiri population, future studies need comprehensive, cohort, and replicative studies with large sample size. |
| Publish Date |
2021-09-23 07:48 |
| Citation |
Rah B, Banday MA, Bhat GR, Shah OJ, Jeelani H, Kawoosa F, Yousuf T, Afroze D. Evaluation of biomarkers, genetic mutations, and epigenetic modifications in early diagnosis of pancreatic cancer. World J Gastroenterol 2021; 27(36): 6093-6109 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i36/6093.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i36.6093 |
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