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Articles Published Processes
10/27/2021 7:14:11 AM | Browse: 567 | Download: 1136
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Received |
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2021-04-11 09:59 |
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Peer-Review Started |
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2021-04-11 10:02 |
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To Make the First Decision |
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Return for Revision |
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2021-06-13 15:37 |
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Revised |
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2021-06-24 19:23 |
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Second Decision |
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2021-09-18 03:29 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-09-19 08:47 |
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Articles in Press |
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2021-09-19 08:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-10-19 08:37 |
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Publish the Manuscript Online |
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2021-10-27 07:14 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Frontier |
Article Title |
Hepatocellular carcinoma risk after viral response in hepatitis C virus-advanced fibrosis: Who to screen and for how long?
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Manuscript Source |
Invited Manuscript |
All Author List |
Adriana Ahumada, Laura Rayón, Clara Usón, Rafael Bañares and Sonia Alonso Lopez |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Sonia Alonso Lopez, MD, PhD, Attending Doctor, Consultant Physician-Scientist, Doctor, Doctor, Senior Researcher, Liver Unit, Hospital General Universitario Gregorio Marañón, Doctor Esquerdo 46, Madrid 28007, Spain. salonsol@telefonica.net |
Key Words |
Hepatitis C virus; Hepatocellular carcinoma; Liver fibrosis; Surveillance; Sustained virologic response; Epigenetic changes; Predictive models; Cost-effectiveness |
Core Tip |
Hepatocellular carcinoma (HCC) risk is reduced after sustained viral response, but a substantial threat persists over time. Understanding the natural history of hepatitis C virus infection and the variable influence of viral eradication in the molecular and epigenetic changes that occur during infection are essential to explain the different risk of developing HCC in patients with advanced fibrosis. The definition of the appropriate tools to estimate the individual risk of HCC after antiviral treatment providing reliable recommendations about HCC surveillance is probably the most important challenge to be clarified in this field. |
Publish Date |
2021-10-27 07:14 |
Citation |
Ahumada A, Rayón L, Usón C, Bañares R, Alonso Lopez S. Hepatocellular carcinoma risk after viral response in hepatitis C virus-advanced fibrosis: Who to screen and for how long? World J Gastroenterol 2021; 27(40): 6737-6749 |
URL |
https://www.wjgnet.com/1007-9327/full/v27/i40/6737.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v27.i40.6737 |
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