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Articles Published Processes
12/30/2021 8:21:52 AM | Browse: 300 | Download: 665
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Received |
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2021-04-26 08:55 |
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Peer-Review Started |
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2021-04-26 08:58 |
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To Make the First Decision |
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Return for Revision |
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2021-05-31 02:20 |
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Revised |
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2021-06-14 16:11 |
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Second Decision |
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2021-08-24 03:19 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-24 09:41 |
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Articles in Press |
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2021-08-24 09:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-11-30 17:34 |
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Typeset the Manuscript |
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2021-12-24 09:13 |
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Publish the Manuscript Online |
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2021-12-30 08:21 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Paradox role of interleukin-33/suppressor of tumorigenicity 2 in colorectal carcinogenesis, progress and therapeutic potential
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fang Huang, Wan-Yuan Chen, Jie Ma, Xiang-Lei He and Jian-Wei Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of China |
81803069 |
| Zhejiang Medical Technology Plan Project |
2019RC007 |
| Zhejiang Medical Technology Plan Project |
2019KY007 |
| Zhejiang Medical Technology Plan Project |
2021KY047 |
| Funds of Science Technology Department of Zhejiang Province |
LGF21H160033 |
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| Corresponding Author |
Jian-Wei Wang, MD, Assistant Professor, Department of Pathology, Laboratory Medicine Center, Zhejiang Provincial Peoples’ Hospital, Peoples’ Hospital of Hangzhou Medical College, No. 158 Shangtang Road, Hangzhou 310014, Zhejiang Province, China. wangjianwei2002@126.com |
| Key Words |
Interleukin 33; Suppressor of tumorigenicity 2 signaling; Tumor microenvironment; Conventional therapies; Colorectal cancer |
| Core Tip |
Interleukin-33 (IL-33) belongs to the IL-1 cytokine family and binds to the suppressor of tumorigenicity 2 (ST2) receptor. IL-33 plays a key role in cancer progression due to interact with cellular components in the inflammatory microenvironment of tumors. Therefore, it is a challenge to design and optimize treatment strategies suitable for colorectal cancer (CRC) based on IL-33/ST2 signal to coordinate tumor microenvironment. IL-33 also has effects on CRC prevention. These findings implicated multifaceted roles of IL-33 in cancer treatment. |
| Publish Date |
2021-12-30 08:21 |
| Citation |
Huang F, Chen WY, Ma J, he X, Wang J. Paradox role of interleukin-33/suppressor of tumorigenicity 2 in colorectal carcinogenesis, progress and therapeutic potential. World J Clin Cases 2022; 10(1): 23-34 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i1/23.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i1.23 |
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