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12/14/2021 3:29:38 AM | Browse: 221 | Download: 635
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 67140
Country/Territory Italy
Received
2021-04-24 11:11
Peer-Review Started
2021-04-24 11:15
To Make the First Decision
Return for Revision
2021-06-14 07:24
Revised
2021-06-25 13:22
Second Decision
2021-12-02 03:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-12-03 06:56
Articles in Press
2021-12-03 06:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-12-08 10:45
Publish the Manuscript Online
2021-12-14 03:29
ISSN 1948-5190 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Efficacy and tolerability of high and low-volume bowel preparation compared: A real-life single-blinded large-population study
Manuscript Source Invited Manuscript
All Author List Vincenzo Occhipinti, Paola Soriani, Francesco Bagolini, Valentina Milani, Emanuele Rondonotti, Maria Laura Annunziata, Flaminia Cavallaro, Sara Vavassori, Maurizio Vecchi, Luca Pastorelli and Gian Eugenio Tontini
ORCID
Author(s) ORCID Number
Vincenzo Occhipinti http://orcid.org/0000-0001-8623-7428
Paola Soriani http://orcid.org/0000-0001-8429-906X
Francesco Bagolini http://orcid.org/0000-0003-4808-6096
Valentina Milani http://orcid.org/0000-0002-2989-981X
Emanuele Rondonotti http://orcid.org/0000-0001-5013-0514
Maria Laura Annunziata http://orcid.org/0000-0002-1012-4117
Flaminia Cavallaro http://orcid.org/0000-0003-3103-1398
Sara Vavassori http://orcid.org/0000-0001-5912-1649
Maurizio Vecchi http://orcid.org/0000-0003-1558-8604
Luca Pastorelli http://orcid.org/0000-0002-2810-9951
Gian Eugenio Tontini http://orcid.org/0000-0002-8964-5686
Funding Agency and Grant Number
Corresponding Author Luca Pastorelli, MD, PhD, Associate Professor, Gastroenterology Unit, IRCCS Policlinico San Donato, Piazza Malan, San Donato Milanese 20097, Italy. luca.pastorelli@unimi.it
Key Words Bowel preparation volume; Polyethylene glycol; Bisacodyl; Colonoscopy; Colonic adenomas; Tolerability
Core Tip Quality of bowel preparation is one of the main factors influencing outcomes of colonoscopy. This prospective real-life study compared bowel cleansing (according to the Boston Bowel Preparation Scale), clinically relevant colonoscopy outcomes (lesions detection rate) and tolerability of a standard high-volume bowel preparation and a low-volume preparation (2 L polyethylene glycol + bisacodyl). Even if the two study groups did not show differences in terms of adequate bowel preparation, the use of the high-volume preparation was associated with higher polyp and adenoma detection rates. There were no differences in terms of advanced adenomas, sessile/serrated lesions and cancer detections. Performance of low-volume preparation seems influenced by image resolution of colonoscopes, with fewer lesions detected compared to high-volume when using standard-definition colonoscopes. The two preparations were comparable in terms of patients’ self-reported tolerability, but complete adherence to preparation was more common with the low-volume product.
Publish Date 2021-12-14 03:29
Citation Occhipinti V, Soriani P, Bagolini F, Milani V, Rondonotti E, Annunziata ML, Cavallaro F, Vavassori S, Vecchi M, Pastorelli L, Tontini GE. Efficacy and tolerability of high and low-volume bowel preparation compared: A real-life single-blinded large-population study. World J Gastrointest Endosc 2021; 13(12): 659-672
URL https://www.wjgnet.com/1948-5190/full/v13/i12/659.htm
DOI https://dx.doi.org/10.4253/wjge.v13.i12.659
Full Article (PDF) WJGE-13-659.pdf
Full Article (Word) WJGE-13-659.docx
Manuscript File 67140_Auto_Edited.docx
Answering Reviewers 67140-Answering reviewers.pdf
Audio Core Tip 67140-Audio core tip.aac
Biostatistics Review Certificate 67140-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 67140-Conflict-of-interest statement.pdf
Copyright License Agreement 67140-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 67140-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 67140-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 67140-Language certificate.pdf
Supplementary Material 67140-Supplementary material.pdf
Peer-review Report 67140-Peer-review(s).pdf
Scientific Editor Work List 67140-Scientific editor work list.pdf