Publication Name	World Journal of Gastroenterology
Manuscript ID	6728
Country	China

Received	2013-10-27 22:37
Peer-Review Started	2013-10-28 13:49
To Make the First Decision	2014-01-15 17:07
Return for Revision	2014-01-17 16:32
Revised	2014-03-12 21:07
Second Decision	2014-05-05 08:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-05 09:49
Articles in Press	2014-05-23 11:02
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-19 21:27
Typeset the Manuscript	2014-07-15 18:15
Publish the Manuscript Online	2014-08-07 10:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	CacyBP/SIP nuclear translocation induced by gastrin promotes gastric cancer cell proliferation
Manuscript Source	Invited Manuscript
All Author List	Hui-Hong Zhai, Juan Meng, Jing-Bo Wang, Zhen-Xiong Liu, Yuan-Fei Li and Shan-Shan Feng
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81072040
Corresponding Author	Hui-Hong Zhai, MD, PhD, Department of Digestive Diseases, General Hospital of Ningxia Medical University, 804 Shengli Street, Xingqing Area, Yinchuan 750004, Ningxia Hui Autonomous Region, China. zhaihuihong@263.net
Key Words	Calcyclin binding protein/Siah-1 interacting protein; Gastric caner cells; Nuclear translocation; Gastrin
Core Tip	Calcyclin binding protein, also called Siah-1 interacting protein (CacyBP/SIP), is a component of the ubiquitination pathway. It can translocate to the cell nucleus. In colon cancer cells, it was found that gastrin, epidermal growth factor, prostaglandin E2 and hypoxia can induce CacyBP/SIP nuclear translocation. Our previous study found that CacyBP/SIP-positive staining was observed in the cytoplasm and nuclei of some cancer cells in gastric cancer tissues. Thus, there is considerable interest in determining whether CacyBP/SIP can translocate into the nucleus or not in gastric cancer cells, and whether nuclear translocation of CacyBP/SIP mediates the proliferation of gastric cancer cells.
Publish Date	2014-08-07 10:34
Citation	Zhai HH, Meng J, Wang JB, Liu ZX, Li YF, Feng SS. CacyBP/SIP nuclear translocation induced by gastrin promotes gastric cancer cell proliferation. World J Gastroenterol 2014; 20(29): 10062-10070
URL	http://www.wjgnet.com/1007-9327/full/v20/i29/10062.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i29.10062

Full Article (PDF)	WJG-20-10062.pdf
Full Article (Word)	WJG-20-10062.doc
Manuscript File	6728-Review.doc
Answering Reviewers	6728-Answering reviewers.pdf
Copyright License Agreement	6728-Copyright assignment.pdf
Peer-review Report	6728-Peer review(s).pdf
Scientific Editor Work List	6728-Scientific editor work list.pdf