Publication Name	World Journal of Hepatology
Manuscript ID	67307
Country	United States

Received	2021-04-20 17:38
Peer-Review Started	2021-04-20 17:41
To Make the First Decision
Return for Revision	2021-06-18 21:15
Revised	2021-06-25 19:26
Second Decision	2021-08-24 03:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-08-24 09:49
Articles in Press	2021-08-24 09:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-09-17 03:01
Publish the Manuscript Online	2021-09-22 08:09

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Elevated liver enzymes portends a higher rate of complication and death in SARS-CoV-2
Manuscript Source	Unsolicited Manuscript
All Author List	Emily E Currier, Mohamad Dabaja and Syed-Mohammed Jafri
ORCID	Author(s) ORCID Number Emily E Currier http://orcid.org/0000-0002-9942-6698 Mohamad Dabaja http://orcid.org/0000-0001-5283-9949 Syed-Mohammed Jafri http://orcid.org/0000-0001-8108-7408
Funding Agency and Grant Number
Corresponding Author	Emily E Currier, BSc, Doctor, Doctor, School of Medicine, Wayne State University, 540 E. Canfield, Detroit, MI 48201, United States. emily.currier@med.wayne.edu
Key Words	COVID-19; Hepatology; Liver damage; Complications; Elevated liver function test
Core Tip	This study suggests that in coronavirus disease-2019 (COVID-19) positive patients, those with elevated and super elevated liver function tests (LFTs) have significantly higher odds of hospital admittance, intensive care unit admittance, intubation, and death in comparison to those COVID-19 patients without elevated LFTs (all P < 0.001). LFT elevations may serve as an indicator for medical professionals in the treatment of COVID-19 patients and may allow for proactive treatment of those patients at increased risk of complications.
Publish Date	2021-09-22 08:09
Citation	Currier EE, Dabaja M, Jafri SM. Elevated liver enzymes portends a higher rate of complication and death in SARS-CoV-2. World J Hepatol 2021; 13(9): 1181-1189
URL	https://www.wjgnet.com/1948-5182/full/v13/i9/1181.htm
DOI	https://dx.doi.org/10.4254/wjh.v13.i9.1181

Full Article (PDF)	WJH-13-1181.pdf
Full Article (Word)	WJH-13-1181.docx
Manuscript File	67307_Auto_Edited-JLW.docx
Answering Reviewers	67307-Answering reviewers.pdf
Audio Core Tip	67307-Audio core tip.m4a
Biostatistics Review Certificate	67307-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	67307-Conflict-of-interest statement.pdf
Copyright License Agreement	67307-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document	67307-Institutional review board statement.pdf
Peer-review Report	67307-Peer-review(s).pdf
Scientific Misconduct Check	67307-Scientific misconduct check.pdf
Scientific Editor Work List	67307-Scientific editor work list.pdf
CrossCheck Report	67307-CrossCheck report.pdf