Publication Name	World Journal of Gastroenterology
Manuscript ID	6743
Country	Japan

Received	2013-10-28 11:31
Peer-Review Started	2013-10-29 10:23
To Make the First Decision	2013-12-04 09:22
Return for Revision	2013-12-05 19:09
Revised	2013-12-20 18:02
Second Decision	2014-02-20 09:04
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-02-20 09:33
Articles in Press	2014-05-23 11:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-26 14:07
Publish the Manuscript Online	2014-07-26 13:36

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Therapeutic applications of curcumin for patients with pancreatic cancer
Manuscript Source	Invited Manuscript
All Author List	Masashi Kanai
Funding Agency and Grant Number
Corresponding Author	Masashi Kanai, MD, PhD, Department of Clinical Oncology and Pharmacogenomics, Graduate School of Medicine, Kyoto University Kyoto, Japan Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan. kanai@kuhp.kyoto-u.ac.jp
Key Words	Curcumin; Pancreatic cancer; Nuclear factor-kappa B; Bioavailability; THERACURMIN
Core Tip	A growing body of evidence supports the idea that curcumin is a promising anticancer drug. Curcumin has anticancer effects, both alone and in combination with other anticancer drugs, through the modulation of a variety of molecular targets in preclinical models. However, the poor bioavailability of curcumin has been the major challenge to its clinical application. This problem has been overcome by the development of highly bioavailable forms of curcumin (THERACURMIN?), and higher plasma curcumin levels can now be achieved without increased toxicity. Further clinical trials will be necessary to test the therapeutic applications of this promising agent in patients with pancreatic cancer.
Publish Date	2014-07-26 13:36
Citation	Kanai M. Therapeutic applications of curcumin for patients with pancreatic cancer. World J Gastroenterol 2014; 20(28): 9384-9391
URL	http://www.wjgnet.com/1007-9327/full/v20/i28/9384.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i28.9384

Full Article (PDF)	WJG-20-9384.pdf
Full Article (Word)	WJG-20-9384.doc
Manuscript File	6743-Review.doc
Answering Reviewers	6743-Answering reviewers.pdf
Copyright License Agreement	6743-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6743-Language certificate.pdf
Peer-review Report	6743-Peer reviewer(s).pdf
Scientific Editor Work List	6743-Scientific editor work list.doc