Publication Name	World Journal of Gastroenterology
Manuscript ID	6749
Country	Sweden

Received	2013-10-28 13:19
Peer-Review Started	2013-10-29 09:12
To Make the First Decision	2014-04-15 18:26
Return for Revision	2014-04-15 19:29
Revised	2014-04-27 05:17
Second Decision	2014-06-05 10:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-05 11:02
Articles in Press	2014-06-05 11:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-10-16 09:32
Publish the Manuscript Online	2014-10-29 19:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Gastrointestinal dysfunction in liver cirrhosis
Manuscript Source	Invited Manuscript
All Author List	Evangelos Kalaitzakis
Funding Agency and Grant Number
Corresponding Author	Evangelos Kalaitzakis, MD, PhD, FEBGH, Associate Professor, Department of Gastroenterology, Skåne University Hospital, University of Lund, 22185 Lund, Sweden. evangelos.kalaitzakis@medicine.gu.se
Key Words	Liver cirrhosis; Gut motility; Gastric accommodation; Malnutrition; Gastrointestinal symptoms; Intestinal permeability
Core Tip	Features of gut dysfunction are common in patients with cirrhosis and may have an impact on quality of life and nutritional status as well as contribute to the development of cirrhosis complications. Cirrhotic patients often report gastrointestinal symptoms. Their pathophysiology is complex, probably involving factors related to liver disease severity, psychological distress, and increased gastric sensitivity to distension as well as delayed gut transit. The latter is common in cirrhosis and may be related to postprandial glucose and hormone disturbances due to insulin resistance. Intestinal barrier dysfunction, potentially leading to bacterial translocation and permeation of bacterial products, has been frequently reported in cirrhotic patients, especially those with portal hypertension.
Publish Date	2014-10-29 19:34
Citation	Kalaitzakis E. Gastrointestinal dysfunction in liver cirrhosis. World J Gastroenterol 2014; 20(40): 14686-14695
URL	http://www.wjgnet.com/1007-9327/full/v20/i40/14686.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i40.14686

Full Article (PDF)	WJG-20-14686.pdf
Full Article (Word)	WJG-20-14686.doc
Manuscript File	6749-Review.docx
Answering Reviewers	6749-Answering reviewers.pdf
Copyright License Agreement	6749-Copyright assignment.pdf
Peer-review Report	6749-Peer review(s).pdf
Scientific Misconduct Check	6749-CrossCheck.jpg
Scientific Editor Work List	6749-Scientific editor work list.pdf