Publication Name	World Journal of Gastroenterology
Manuscript ID	6751
Country	China

Received	2013-10-28 13:30
Peer-Review Started	2013-10-28 20:36
To Make the First Decision	2013-12-16 18:14
Return for Revision	2013-12-20 16:34
Revised	2014-01-02 22:01
Second Decision	2014-03-13 13:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-03-13 16:46
Articles in Press	2014-05-23 11:23
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-04-18 11:41
Typeset the Manuscript	2014-05-30 14:16
Publish the Manuscript Online	2014-07-03 15:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Peroxisome proliferator-activated receptor α, a potential therapeutic target for alcoholic liver disease
Manuscript Source	Invited Manuscript
All Author List	Yue-Min Nan, Rong-Qi Wang and Na Fu
Funding Agency and Grant Number
Corresponding Author	Yue-Min Nan, MD, PhD, Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, 139 Ziqiang Road, Shijiazhuang 050051, Hebei Province, China. nanyuemin@163.com
Key Words	Alcoholic liver disease; Oxidative stress; Inflammation; Fibrosis; Peroxisome proliferator-activated receptor α
Core Tip	Alcoholic liver disease (ALD) is among the most common chronic liver disease. Modulation of therapeutic genes could potentially provide a novel and more effective treatment option. In this paper, we summarized the potential therapeutic role of PPARα modulation and illustrated the mechanism of PPARα in modulation of hepatic lipid metabolism, oxidative stress, inflammatory response and fibrogenesis in alcoholic liver disease. It is identified that PPARα agonists may serve as an effective therapeutic strategy for ALD.
Publish Date	2014-07-03 15:30
Citation	Nan YM, Wang RQ, Fu N. Peroxisome proliferator-activated receptor α, a potential therapeutic target for alcoholic liver disease. World J Gastroenterol 2014; 20(25): 8055-8060
URL	http://www.wjgnet.com/1007-9327/full/v20/i25/8055.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i25.8055

Full Article (PDF)	WJG-20-8055.pdf
Full Article (Word)	WJG-20-8055.doc
Manuscript File	6751-Review.doc
Answering Reviewers	6751-Answering reviewers.pdf
Copyright License Agreement	6751-Copyright assignment.pdf
Peer-review Report	6751-Peer reviewer(s).pdf
Scientific Editor Work List	6751-Scientific editor work list.doc