Publication Name	World Journal of Gastroenterology
Manuscript ID	6752
Country	Italy

Received	2013-10-28 13:33
Peer-Review Started	2013-10-28 20:19
To Make the First Decision	2013-12-26 11:33
Return for Revision	2014-01-02 16:31
Revised	2014-02-14 23:49
Second Decision	2014-04-16 11:06
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-16 12:22
Articles in Press	2014-05-23 11:02
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-08 15:48
Typeset the Manuscript	2014-07-03 12:49
Publish the Manuscript Online	2014-07-21 17:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Neurological disorders and inflammatory bowel diseases
Manuscript Source	Invited Manuscript
All Author List	Giovanni Casella, Gian Eugenio Tontini, Gabrio Bassotti, Luca Pastorelli, Vincenzo Villanacci, Luisa Spina, Vittorio Baldini and Maurizio Vecchi
Funding Agency and Grant Number
Corresponding Author	Maurizio Vecchi, MD, Gastroenterology and Gastrointestinal Endoscopy Unit, IRCCS Policlinico San Donato, via Morandi 30, 20097 San Donato Milanese, Italy. maurizio.vecchi@unimi.it
Key Words	Inflammatory bowel diseases; Crohn’s disease; Ulcerative colitis; Extraintestinal manifestations; Neurological disorders; Multiple sclerosis; Progressive multifocal encephalopathy; Demyelinating neuropathies; Cerebrovascular diseases; Side effects
Core Tip	Extraintestinal manifestations occur in about one-third of patients with inflammatory bowel disease (IBD) and may precede the onset of gastrointestinal symptoms by many years. Neurological disorders are uncommon in IBD but they can represent an important cause of morbidity and relevant diagnostic issue. Furthermore, the use of immunosuppressant and biological therapies for IBD may also play a pivotal role in the development of neurological disorders. Hence, we review the main features of neurological complications associated with IBD, with particular reference to those related to drugs, thereby focusing on their clinical presentation and possible pathophysiological mechanisms.
Publish Date	2014-07-21 17:17
Citation	Casella G, Tontini GE, Bassotti G, Pastorelli L, Villanacci V, Spina L, Baldini V, Vecchi M. Neurological disorders and inflammatory bowel diseases. World J Gastroenterol 2014; 20(27): 8764-8782
URL	http://www.wjgnet.com/1007-9327/full/v20/i27/8764.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i27.8764

Full Article (PDF)	WJG-20-8764.pdf
Full Article (Word)	WJG-20-8764.doc
Manuscript File	6752-Review.doc
Answering Reviewers	6752-Answering reviewers.pdf
Copyright License Agreement	6752-Copyright assignment.pdf
Peer-review Report	6752-Peer reviewer(s).pdf
Scientific Editor Work List	6752-Scientific editor work list.doc