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Articles Published Processes
1/21/2022 9:46:26 AM | Browse: 452 | Download: 1084
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Received |
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2021-04-28 21:57 |
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Peer-Review Started |
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2021-04-28 22:00 |
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To Make the First Decision |
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Return for Revision |
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2021-07-08 07:23 |
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Revised |
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2021-08-05 23:34 |
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Second Decision |
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2021-12-20 03:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-12-23 05:56 |
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Articles in Press |
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2021-12-23 05:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-12-16 21:31 |
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Typeset the Manuscript |
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2022-01-20 07:10 |
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Publish the Manuscript Online |
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2022-01-21 09:46 |
ISSN |
2219-2824 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Immunology |
Manuscript Type |
Minireviews |
Article Title |
Historical evolution, overview, and therapeutic manipulation of co-stimulatory molecules
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Henry Velazquez-Soto, Fernanda Real and Maria C Jiménez-Martínez |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Institute of Ophthalmology “Fundación Conde de Valenciana” |
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Velazquez-Soto H received fellowship 294674 from CONACYT during his doctoral studies in Programa de Doctorado en Ciencias Médicas, Odontológicas y de la Salud (Farmacología Clínica), Universidad Nacional Autónoma de México (UNAM) |
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Real F with CVU 917729, recieved fellowship from CONACYT during his master studies in Programa de Maestría en Ciencias Médicas, Odontológicas y de la Salud (Farmacología Clínica), Universidad Nacional Autónoma de México (UNAM) |
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Corresponding Author |
Maria C Jiménez-Martínez, MD, PhD, Chief Doctor, Department of Immunology and Research Unit, Institute of Ophthalmology “Conde de Valenciana”, Chimalpopoca 14, Col. Obrera, Del. Cuauhtemoc, Mexico City 06800, Mexico. mcjimenezm@institutodeoftalmologia.org |
Key Words |
Co-stimulatory molecules; Immune modulation; Monoclonal antibodies; Biological therapy; Autoimmune diseases; Oncological diseases |
Core Tip |
Several reviews of co-stimulatory molecules have been published. However, this review summarizes the historical aspects, the cellular and molecular mechanisms of the different families of costimulatory molecules implied in processes of health and disease. All this knowledge has been applied to develop different drugs targeting costimulatory molecules in different diseases like cancer and autoimmune diseases. |
Publish Date |
2022-01-21 09:46 |
Citation |
Velazquez-Soto H, Real F, Jiménez-Martínez MC. Historical evolution, overview, and therapeutic manipulation of co-stimulatory molecules. World J Immunol 2022; 12(1): 1-8 |
URL |
https://www.wjgnet.com/2219-2824/full/v12/i1/1.htm |
DOI |
https://dx.doi.org/10.5411/wji.v12.i1.1 |
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