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Articles Published Processes
11/25/2021 8:31:20 AM | Browse: 491 | Download: 1265
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Received |
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2021-05-05 16:02 |
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Peer-Review Started |
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2021-05-05 16:03 |
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To Make the First Decision |
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Return for Revision |
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2021-06-23 14:50 |
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Revised |
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2021-06-25 11:27 |
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Second Decision |
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2021-10-15 06:33 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-10-15 08:59 |
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Articles in Press |
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2021-10-15 08:59 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-09-29 03:52 |
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Typeset the Manuscript |
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2021-11-22 05:02 |
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Publish the Manuscript Online |
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2021-11-25 08:31 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Physiology |
| Manuscript Type |
Basic Study |
| Article Title |
ARPE-19 conditioned medium promotes neural differentiation of adipose-derived mesenchymal stem cells
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Giuliana Mannino, Martina Cristaldi, Giovanni Giurdanella, Rosario Emanuele Perrotta, Debora Lo Furno, Rosario Giuffrida and Dario Rusciano |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| University of Catania, Italy, “Piano Triennale per la Ricerca 2020-2022–Grant PIACERI, project “NanoRet” |
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| Corresponding Author |
Debora Lo Furno, PhD, Assistant Professor, Department of Biomedical and Biotechnological Sciences, University of Catania, Via Santa Sofia 97, Catania 95123, CT, Italy. lofurno@unict.it |
| Key Words |
Adipose-derived mesenchymal stem cells; Retinal pigment epithelium; Neural markers; Neural differentiation; Retina damage; Cell-based medicine |
| Core Tip |
Neural-like differentiation of adipose-derived stem cells (ASCs) was tested using a conditioned medium from ARPE-19 cells, a cell line derived from human retinal pigment epithelium. Following this treatment, the expression of typical glial and neuronal markers increased in a time-dependent manner. Neural-like differentiated ASCs may represent a valuable tool for cell-based therapeutic approaches in the field of regenerative medicine for the treatment of eye diseases. |
| Publish Date |
2021-11-25 08:31 |
| Citation |
Mannino G, Cristaldi M, Giurdanella G, Perrotta RE, Lo Furno D, Giuffrida R, Rusciano D. ARPE-19 conditioned medium promotes neural differentiation of adipose-derived mesenchymal stem cells. World J Stem Cells 2021; 13(11): 1783-1796 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i11/1783.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i11.1783 |
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