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Articles Published Processes
12/14/2021 11:58:13 PM | Browse: 232 | Download: 513
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Received |
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2021-05-11 09:53 |
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Peer-Review Started |
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2021-05-11 09:57 |
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To Make the First Decision |
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Return for Revision |
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2021-06-14 09:38 |
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Revised |
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2021-06-24 10:27 |
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Second Decision |
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2021-09-13 02:21 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-09-17 01:08 |
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Articles in Press |
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2021-09-17 01:08 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-12-06 08:31 |
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Publish the Manuscript Online |
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2021-12-14 23:58 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
MutL homolog 1 methylation and microsatellite instability in sporadic colorectal tumors among Filipinos
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Loraine Kay D Cabral, Cynthia A Mapua, Filipinas F Natividad, Caecilia H C Sukowati, Edgardo R Cortez and Ma Luisa D Enriquez |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Department of Science and Technology and the Philippine Council for Health Research and Development (DOST-PCHRD) |
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| St. Luke’s Medical Center, Manila, Philippines |
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| Regione Autonomo FVG in Progetti Internazionali 2021 to the FIF |
DGR 189 dd 12/2/21 |
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| Corresponding Author |
Loraine Kay D Cabral, BSc, MSc, Research Associate, Research and Biotechnology Group, St. Luke's Medical Center, 279 E Rodriguez Sr. Avenue, Quezon City 1112, Philippines. kay.cabral@fegato.it |
| Key Words |
Sporadic colorectal cancer; DNA methylation; Microsatellite instability; Population genetic; Colorectal cancer |
| Core Tip |
Colorectal cancer (CRC) ranks third in terms of incidence and second in mortality worldwide. In CRC, the silencing of mismatch repair genes, including the mutL homolog 1 (hMLH1) has been linked to microsatellite instability (MSI). This study investigated the status of hMLH1 methylation and MSI in normal and tumor tissues of Filipinos sporadic CRC patients and their clinical significances. |
| Publish Date |
2021-12-14 23:58 |
| Citation |
Cabral LKD, Mapua CA, Natividad FF, Sukowati CHC, Cortez ER, Enriquez MLD. MutL homolog 1 methylation and microsatellite instability in sporadic colorectal tumors among Filipinos. World J Gastrointest Oncol 2021; 13(12): 2101-2113 |
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i12/2101.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i12.2101 |
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