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Articles Published Processes
7/26/2021 11:20:59 AM | Browse: 582 | Download: 1304
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Received |
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2021-05-07 07:08 |
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Peer-Review Started |
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2021-05-07 07:10 |
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To Make the First Decision |
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Return for Revision |
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2021-06-06 03:50 |
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Revised |
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2021-06-15 23:08 |
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Second Decision |
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2021-07-08 00:21 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-09 08:39 |
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Articles in Press |
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2021-07-09 08:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-07-20 14:04 |
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Publish the Manuscript Online |
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2021-07-26 11:20 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
HER2-positive adenocarcinoma arising from heterotopic pancreas tissue in the duodenum: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yoshirumi S Hirokawa, Takashi Iwata, Yoshinaga Okugawa, Koji Tanaka, Hiroyuki Sakurai and Masatoshi Watanabe |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yoshirumi S Hirokawa, MD, PhD, Lecturer, Department of Oncologic Pathology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 5148507, Japan. ultray2k@med.mie-u.ac.jp |
| Key Words |
Heterotopic pancreas tissue; Duodenal cancer; Human epidermal growth factor receptor 2; Trastuzumab; Conversion surgery; Case report |
| Core Tip |
Adenocarcinoma that develops from heterotopic pancreas tissue in the duodenum is a very rare disease. Therefore, standard chemotherapy regimens to treat these patients have not been established. A 65-year-old woman presented with unresectable duodenal cancer with HER2 overexpression. Because the patient responded well to trastuzumab chemotherapy, pancreatoduodenectomy was performed. Histology and immunohistochemistry assessments revealed that the cancer developed from heterotopic pancreas tissue in the duodenum. The findings of this case suggest that HER2 status should be examined in duodenal adenocarcinoma to determine the indication for targeted therapy. Trastuzumab chemotherapy is effective for heterotopic pancreatic adenocarcinoma but not orthotopic pancreatic cancer. |
| Publish Date |
2021-07-26 11:20 |
| Citation |
Hirokawa YS, Iwata T, Okugawa Y, Tanaka K, Sakurai H, Watanabe M. HER2-positive adenocarcinoma arising from heterotopic pancreas tissue in the duodenum: A case report. World J Gastroenterol 2021; 27(28): 4738-4745 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i28/4738.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i28.4738 |
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