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Articles Published Processes
9/10/2021 12:09:57 PM | Browse: 588 | Download: 1268
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Received |
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2021-05-08 00:24 |
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Peer-Review Started |
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2021-05-08 00:27 |
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To Make the First Decision |
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Return for Revision |
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2021-06-16 01:41 |
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Revised |
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2021-06-29 08:56 |
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Second Decision |
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2021-07-29 02:54 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-29 07:32 |
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Articles in Press |
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2021-07-29 07:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-08-09 04:02 |
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Typeset the Manuscript |
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2021-08-19 00:59 |
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Publish the Manuscript Online |
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2021-09-10 12:09 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Characterization of metabolic landscape in hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jing Wu, Ran Xue, Rong-Tao Jiang and Qing-Hua Meng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Municipal Natural Science Foundation of Beijing, China |
7192085 |
| National Science and Technology Major Project of China |
2018ZX10302206-003-007 |
| National Science and Technology Major Project of China |
2017ZX10203202-001-005 |
| The Capital Health Research and Development of Special |
2018-1-3011 |
| National Natural Science Foundation of China |
81470877 |
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| Corresponding Author |
Qing-Hua Meng, MD, Chief Physician, Professor, Department of Medical Oncology, Beijing You-An Hospital, Capital Medical University, No. 8, Xi Tou Tiao, Youanmen Wai, Fengtai District, Beijing 100069, China. meng_qh0805@ccmu.edu.cn |
| Key Words |
Hepatocellular carcinoma; Metabolic reprogramming; Glycolysis; Lipid metabolism; Glutamine addiction; Diagnosis and treatment |
| Core Tip |
Metabolic activities play a crucial role in promoting tumor transformation and progression. In the current review, we present a summary of recent advances investigating the metabolic traits of hepatocellular carcinoma (HCC) with a specific focus on three common metabolic alterations involving glycolysis, lipid metabolism, and glutamine addiction, and describe some representative diagnostic markers or tools, and promising treatment agents. Moreover, challenges related to the existence of great heterogeneity in HCC, the ignorance of study-related confounders, and a lack of validation of proposed markers are discussed. |
| Publish Date |
2021-09-10 12:09 |
| Citation |
Wu J, Xue R, Jiang RT, Meng QH. Characterization of metabolic landscape in hepatocellular carcinoma. World J Gastrointest Oncol 2021; 13(9): 1144-1156 |
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i9/1144.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i9.1144 |
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