Publication Name	World Journal of Diabetes
Manuscript ID	68066
Country	Iraq

Received	2021-05-10 20:25
Peer-Review Started	2021-05-10 20:25
To Make the First Decision
Return for Revision	2021-09-05 07:37
Revised	2021-09-07 08:01
Second Decision	2022-04-19 02:08
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-04-26 04:51
Articles in Press	2022-04-26 04:51
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-04-02 23:05
Typeset the Manuscript	2022-04-30 13:40
Publish the Manuscript Online	2022-05-13 10:36

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Endocrinology & Metabolism
Manuscript Type	Letter to the Editor
Article Title	Concomitant dysregulation of androgen secretion and dysfunction of adipose tissue induced insulin resistance
Manuscript Source	Invited Manuscript
All Author List	Marwan SM Al-Nimer
ORCID	Author(s) ORCID Number Marwan SM Al-Nimer http://orcid.org/0000-0002-5336-3353
Funding Agency and Grant Number
Corresponding Author	Marwan SM Al-Nimer, BM BCh, MD, PhD, Professor, Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Diyala, University Street, Baqubah 32001, Diyala, Iraq. alnimermarwan@ymail.com
Key Words	Hyperandrogenism; Hyperinsulinism; Central triggers; Polycystic ovary disease
Core Tip	There is a close relationship between hyperinsulinemia and androgen excess in patients with androgen excess disorders. These disorders result from the dysfunction of gonad and adipose cells under the influence of a specific trigger. Sodium valproate is an example of an external trigger that produces concomitant hyperinsulinemia and androgenism leading to polycystic ovary syndrome. Therefore, elimination of the triggers can lead to recovery from antiepileptic drugs while using insulin sensitizers and/or anti-androgens can help to solve this pathological problem.
Publish Date	2022-05-13 10:36
Citation	Al-Nimer MS. Concomitant dysregulation of androgen secretion and dysfunction of adipose tissue induced insulin resistance. World J Diabetes 2022; 13(5): 417-419
URL	https://www.wjgnet.com/1948-9358/full/v13/i5/417.htm
DOI	https://dx.doi.org/10.4239/wjd.v13.i5.417

Full Article (PDF)	WJD-13-417.pdf
Full Article (Word)	WJD-13-417.docx
Manuscript File	68066_Auto_Edied_LM.docx
Answering Reviewers	68066-Answering reviewers.pdf
Audio Core Tip	68066-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	68066-Conflict-of-interest statement.pdf
Copyright License Agreement	68066-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	68066-Language certificate.pdf
Peer-review Report	68066-Peer-review(s).pdf
Scientific Misconduct Check	68066-Bing-Wang JJ-2.png
Scientific Editor Work List	68066-Scientific editor work list.pdf
CrossCheck Report	68066-CrossCheck report.pdf