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Articles Published Processes
11/10/2021 1:44:24 AM | Browse: 308 | Download: 800
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Received |
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2021-06-06 17:10 |
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Peer-Review Started |
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2021-06-06 17:13 |
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To Make the First Decision |
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Return for Revision |
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2021-06-25 09:52 |
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Revised |
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2021-07-09 01:54 |
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Second Decision |
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2021-09-13 02:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-09-16 22:35 |
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Articles in Press |
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2021-09-16 22:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-10-29 08:32 |
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Publish the Manuscript Online |
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2021-11-10 01:44 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Case Report |
| Article Title |
Next-generation sequencing technology for diagnosis and efficacy evaluation of a patient with visceral leishmaniasis: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhou-Ning Lin, Yong-Cheng Sun, Jia-Ping Wang, Yan-Li Lai and Li-Xia Sheng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Nature Science Foundation of China |
81401321 |
| Basic Public Welfare Research Project of Zhejiang Province |
LGF19H080002 |
| Science Research Project of Medicine and Hygiene of Zhejiang Province |
2018PY052 |
| Public Welfare Science and Technology Project of Ningbo |
2019C50068 |
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| Corresponding Author |
Li-Xia Sheng, PhD, Chief Doctor, Department of Hematology, Ningbo First Hospital, No. 59, Liuting Street, Haishu District, Ningbo 315000, Zhejiang Province, China. slx800408@163.com |
| Key Words |
Visceral leishmaniasis; Kala-azar; Next-generation sequencing; Hemophagocytic lymphohistiocytosis; Diagnosis; Case report |
| Core Tip |
Visceral leishmaniasis (VL) is an easily overlooked parasitic disease because of its low incidence and atypical clinical manifestations. Here, we report a case of imported VL. Initially, no Leishmania was found in the bone marrow or by spleen biopsy. Leishmania was finally confirmed by metagenomic next-generation sequencing (mNGS) analysis of peripheral blood. Finally, after treatment with amphotericin B, the patient recovered well, and various indicators gradually returned to normal during the follow-up period. As a rapid and accurate detection method, mNGS can be used as an alternative method to diagnose and evaluate suspicious cases. |
| Publish Date |
2021-11-10 01:44 |
| Citation |
Lin ZN, Sun YC, Wang JP, Lai YL, Sheng LX. Next-generation sequencing technology for diagnosis and efficacy evaluation of a patient with visceral leishmaniasis: A case report. World J Clin Cases 2021; 9(32): 9903-9910 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i32/9903.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i32.9903 |
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