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11/10/2021 1:44:24 AM | Browse: 201 | Download: 388
Publication Name World Journal of Clinical Cases
Manuscript ID 68125
Country China
Received
2021-06-06 17:10
Peer-Review Started
2021-06-06 17:13
To Make the First Decision
Return for Revision
2021-06-25 09:52
Revised
2021-07-09 01:54
Second Decision
2021-09-13 02:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-09-16 22:35
Articles in Press
2021-09-16 22:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-10-29 08:32
Publish the Manuscript Online
2021-11-10 01:44
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Case Report
Article Title Next-generation sequencing technology for diagnosis and efficacy evaluation of a patient with visceral leishmaniasis: A case report
Manuscript Source Unsolicited Manuscript
All Author List Zhou-Ning Lin, Yong-Cheng Sun, Jia-Ping Wang, Yan-Li Lai and Li-Xia Sheng
ORCID
Author(s) ORCID Number
Zhou-Ning Lin http://orcid.org/0000-0003-1491-2708
Yong-Cheng Sun http://orcid.org/0000-0002-8998-5680
Jia-Ping Wang http://orcid.org/0000-0002-6749-3562
Yan-Li Lai http://orcid.org/0000-0001-9993-5364
Li-Xia Sheng http://orcid.org/0000-0003-0631-7140
Funding Agency and Grant Number
Funding Agency Grant Number
National Nature Science Foundation of China 81401321
Basic Public Welfare Research Project of Zhejiang Province LGF19H080002
Science Research Project of Medicine and Hygiene of Zhejiang Province 2018PY052
Public Welfare Science and Technology Project of Ningbo 2019C50068
Corresponding Author Li-Xia Sheng, PhD, Chief Doctor, Department of Hematology, Ningbo First Hospital, No. 59, Liuting Street, Haishu District, Ningbo 315000, Zhejiang Province, China. slx800408@163.com
Key Words Visceral leishmaniasis; Kala-azar; Next-generation sequencing; Hemophagocytic lymphohistiocytosis; Diagnosis; Case report
Core Tip Visceral leishmaniasis (VL) is an easily overlooked parasitic disease because of its low incidence and atypical clinical manifestations. Here, we report a case of imported VL. Initially, no Leishmania was found in the bone marrow or by spleen biopsy. Leishmania was finally confirmed by metagenomic next-generation sequencing (mNGS) analysis of peripheral blood. Finally, after treatment with amphotericin B, the patient recovered well, and various indicators gradually returned to normal during the follow-up period. As a rapid and accurate detection method, mNGS can be used as an alternative method to diagnose and evaluate suspicious cases.
Publish Date 2021-11-10 01:44
Citation Lin ZN, Sun YC, Wang JP, Lai YL, Sheng LX. Next-generation sequencing technology for diagnosis and efficacy evaluation of a patient with visceral leishmaniasis: A case report. World J Clin Cases 2021; 9(32): 9903-9910
URL https://www.wjgnet.com/2307-8960/full/v9/i32/9903.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i32.9903
Full Article (PDF) WJCC-9-9903.pdf
Full Article (Word) WJCC-9-9903.docx
CARE Checklist–2016 68125-CARE-Checklist–2016-revision.pdf
Manuscript File 68125_Auto_Edited.docx
Answering Reviewers 68125-Answering reviewers.pdf
Audio Core Tip 68125-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 68125-Conflict-of-interest statement.pdf
Copyright License Agreement 68125-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 68125-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 68125-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 68125-Language certificate.pdf
Peer-review Report 68125-Peer-review(s).pdf
Scientific Misconduct Check 68125-Bing-Gong ZM-1.png
Scientific Misconduct Check 68125-Bing-Chang KL-2.jpg
Scientific Editor Work List 68125-Scientific editor work list.pdf