| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Oxaliplatin-induced neuropathy and colo-rectal cancer patient’s quality of life: Practical lessons from a prospective cross-sectional, real-world study
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Iulian Prutianu, Teodora Alexa-Stratulat, Elena Octaviana Cristea, Andrei Nicolau, Diana Cornelia Moisuc, Alina Alexandra Covrig, Karina Ivanov, Adina Emilia Croitoru, Monica Ionela Miron, Mihaela Ioana Dinu, Anca Viorica Ivanov, Mihai Vasile Marinca, Iulian Radu and Bogdan Gafton |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Teodora Alexa-Stratulat, MD, PhD, Assistant Professor, Medical Oncology-Radiotherapy, University of Medicine and Pharmacy Grigore T Popa Iasi, Independentei Street No. 16, Iasi 700483, Romania. teodora.alexa-stratulat@umfiasi.ro |
| Key Words |
Colorectal cancer; Oxaliplatin; Neuropathy; Quality of Life; Recurrence-free survival; Cross-sectional study |
| Core Tip |
Oxaliplatin-induced neuropathy (OIN) is a serious acute and chronic complication of colorectal cancer chemotherapy. This study aims to offer a real-world perspective on the incidence of acute OIN during chemotherapy and its impact on the quality of life. We found that more than 50% of colon cancer patients discontinue chemotherapy, and the main reason is neuropathy. Also, individuals with neuropathy have a lower quality of life, independent of other factors. All in all, as the number of cancer survivors increases, guidelines should be reviewed in order to minimize the risk of chronic OIN as much as possible. |
| Publish Date |
2022-03-29 11:40 |
| Citation |
Prutianu I, Alexa-Stratulat T, Cristea EO, Nicolau A, Moisuc DC, Covrig AA, Ivanov K, Croitoru AE, Miron MI, Dinu MI, Ivanov AV, Marinca MV, Radu I, Gafton B. Oxaliplatin-induced neuropathy and colo-rectal cancer patient’s quality of life: Practical lessons from a prospective cross-sectional, real-world study. World J Clin Cases 2022; 10(10): 3101-3112 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i10/3101.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i10.3101 |
