Publication Name	World Journal of Gastroenterology
Manuscript ID	6825
Country	China

Received	2013-10-29 12:18
Peer-Review Started	2013-10-30 08:55
To Make the First Decision	2013-12-26 11:35
Return for Revision	2013-12-27 15:42
Revised	2014-01-03 16:49
Second Decision	2014-02-27 11:21
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-02-27 11:26
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-29 21:39
Typeset the Manuscript	2014-04-18 19:25
Publish the Manuscript Online	2014-05-14 10:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Autobiography
Article Title	Growth inhibition of hepatocellular carcinoma tumor endothelial cells by miR-204-3p and underlying mechanism
Manuscript Source	Invited Manuscript
All Author List	Zhong-Hui Cui, Shi-Qiang Shen, Zu-Bing Chen and Chao Hu
Funding Agency and Grant Number
Corresponding Author	Shi-Qiang Shen, MD, Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China. swsw2212@sina.com
Key Words	Tumor vascular endothelial cells of hepatocellular carcinoma; Hepatic sinusoidal endothelial cells; MiRNA microarray; Mir-204-3p; Fibronectin 1
Core Tip	This study first employed a microarray to detect differentially expressed miRNAs in hepatocellular carcinoma (HCC) tumor endothelial cells (TECs), as compared to hepatic sinusoidal endothelial cells with the goal of identifying specific miRNAs that play important roles in the angiogenesis of HCC. Our study proved that fibronectin 1 (FN1) is a potential target gene of miR-204-3p, suggesting that FN1 regulates the growth of HCC TECs via the miR-204-3p/FN1 signaling pathway. The underlying mechanism was also investigated to provide new targets and a theoretical basis for the anti-angiogenic gene therapy of HCC.
Publish Date	2014-05-14 10:58
Citation	Cui ZH, Shen SQ, Chen ZB, Hu C. Growth inhibition of hepatocellular carcinoma tumor endothelial cells by miR-204-3p and underlying mechanism. World J Gastroenterol 2014; 20(18): 5493-5504
URL	http://www.wjgnet.com/1007-9327/full/v20/i18/5493.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i18.5493

Full Article (PDF)	WJG-20-5493.pdf
Full Article (Word)	WJG-20-5493.doc
Manuscript File	6825-Review.doc
Answering Reviewers	6825-Answering reviewers.pdf
Copyright License Agreement	6825-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6825-Language certificate.doc
Peer-review Report	6825-Peer review(s).pdf
Scientific Editor Work List	6825-Scientific editor work list.doc