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Articles Published Processes
3/3/2022 6:59:41 AM | Browse: 511 | Download: 1056
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Received |
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2021-05-19 11:29 |
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Peer-Review Started |
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2021-05-19 11:33 |
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To Make the First Decision |
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Return for Revision |
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2021-06-24 18:21 |
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Revised |
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2021-07-04 09:48 |
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Second Decision |
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2022-01-25 03:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-01-26 22:21 |
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Articles in Press |
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2022-01-26 22:21 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-02-22 07:28 |
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Publish the Manuscript Online |
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2022-03-03 06:59 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Minireviews |
| Article Title |
Dualistic role of platelets in living donor liver transplantation: Are they harmful?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chen Liang, Kazuhiro Takahashi, Kinji Furuya, Nobuhiro Ohkohchi and Tatsuya Oda |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Kazuhiro Takahashi, MD, PhD, Assistant Professor, Surgeon, Gastrointestinal and Hepatobiliary-Pancreatic Surgery, University of Tsukuba, Tennodai 1-1-1, Tsukuba 3058575, Ibaraki, Japan. kazu1123@md.tsukuba.ac.jp |
| Key Words |
Platelet; Liver transplantation; Regeneration; Ischemia/reperfusion injury; Kupffer cell; Oxidative stress |
| Core Tip |
Perioperative thrombocytopenia is considered to be associated with poor graft regeneration and postoperative morbidity in the short and long term after living donor liver transplantation (LDLT). This review presented recent evidence for the role of platelets in LDLT based on clinical and basic studies. Platelets have both beneficial and detrimental effects on liver grafts, with a generally positive role in liver regeneration and a potentially negative role in ischemia/reperfusion injury. As increasing perioperative platelet counts are suggested to improve graft regeneration and survival, “platelet therapy” may provide prophylactic or therapeutic strategies to enhance the beneficial effects of LDLT. |
| Publish Date |
2022-03-03 06:59 |
| Citation |
Liang C, Takahashi K, Furuya K, Ohkohchi N, Oda T. Dualistic role of platelets in living donor liver transplantation: Are they harmful? World J Gastroenterol 2022; 28(9): 897-908 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i9/897.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i9.897 |
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