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Articles Published Processes
8/25/2014 5:12:00 PM | Browse: 1095 | Download: 1124
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Received |
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2013-10-29 13:24 |
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Peer-Review Started |
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2013-10-29 18:15 |
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To Make the First Decision |
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2013-12-16 17:40 |
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Return for Revision |
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2013-12-18 15:55 |
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Revised |
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2014-01-27 21:37 |
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Second Decision |
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2014-04-16 11:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-04-16 12:21 |
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Articles in Press |
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2014-05-23 10:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-06-25 15:56 |
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Publish the Manuscript Online |
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2014-07-21 17:17 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Bone marrow derived stem cells for the treatment of end-stage liver disease
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Manuscript Source |
Invited Manuscript |
All Author List |
Cristina Margini, Ranka Vukotic, Lucia Brodosi, Mauro Bernardi and Pietro Andreone |
Funding Agency and Grant Number |
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Corresponding Author |
Pietro Andreone, MD, Professor of Internal Medicine, Dipartimento di Scienze mediche e Chirurgiche, Unità Operativa di Semeiotica Medica, University of Bologna, Padiglione 11, Via Massarenti 9, 40138 Bologna, Italy. pietro.andreone@unibo.it |
Key Words |
Liver cirrhosis; Liver regeneration; Hematopoietic stem cells; Mesenchymal stem cells; End stage liver disease |
Core Tip |
In recent years, the role of bone marrow stem cells (BMSCs) in liver regeneration has been explored in various clinical trials. Because these trials were very diverse, we conducted a descriptive overview to understand the effects of BMSC transplantation on liver histology and morphology, on laboratory parameters and prognostic scores, and finally, on clinical manifestations and quality of life. This overview suggests that the efficacy of BMSC therapy might be temporary, and therefore, repeated cycles of BMSCs could be useful to achieve a sustained benefit. |
Publish Date |
2014-07-21 17:17 |
Citation |
Margini C, Vukotic R, Brodosi L, Bernardi M, Andreone P. Bone marrow derived stem cells for the treatment of end-stage liver disease. World J Gastroenterol 2014; 20(27): 9098-9105 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i27/9098.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i27.9098 |
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