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Articles Published Processes
9/15/2014 6:27:00 PM | Browse: 1160 | Download: 1342
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Received |
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2013-11-01 11:37 |
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Peer-Review Started |
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2013-11-04 08:28 |
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To Make the First Decision |
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2014-01-08 15:04 |
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Return for Revision |
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2014-01-13 10:17 |
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Revised |
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2014-02-10 22:25 |
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Second Decision |
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2014-03-12 18:35 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-03-12 18:42 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-03-28 23:12 |
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Typeset the Manuscript |
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2014-04-20 21:57 |
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Publish the Manuscript Online |
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2014-04-28 14:14 |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Topic Highlights |
Article Title |
Purinergic receptors and nucleotide processing ectoenzymes: Their roles in regulating mesenchymal stem cell functions
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Manuscript Source |
Invited Manuscript |
All Author List |
Sonia Scarfì |
Funding Agency and Grant Number |
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Corresponding Author |
Sonia Scarfì, PhD, Assistant Professor of Molecular Biology, Department of Earth, Environment and Life Sciences, University of Genova, Via Pastore 3, 16132 Genova, Italy. soniascarfi@unige.it |
Key Words |
Mesenchymal stem cell; Purinergic receptors; Ectoenzymes; ATP; -NAD; Adenosine; cADPR |
Core Tip |
The multifaceted aspects of extracellular nucleotide metabolism (mainly ATP and ?-NAD) on mesenchymal stem cell (MSC) surface has been addressed by basic researchers only recently, sometimes revealing unexpected pivotal roles for these molecules in specifying differentiation lineages and modulating MSC physiology and communication with other cells. This review discusses the roles of extracellular nucleotides, their receptors and ectoenzymes, and the relevance of their signaling network and MSC functions, and also focuses on the importance of this emerging area of interest for future MSC-based cell therapies. |
Publish Date |
2014-04-28 14:14 |
Citation |
Scarfì S. Purinergic receptors and nucleotide processing ectoenzymes: Their roles in regulating mesenchymal stem cell functions. World J Stem Cells 2014; 6(2): 153-162 |
URL |
http://www.wjgnet.com/1948-0210/full/v6/i2/153.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v6.i2.153 |
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