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9/1/2014 5:04:00 PM | Browse: 559 | Download: 445
Publication Name World Journal of Gastroenterology
Manuscript ID 6850
Country/Territory Singapore
Received
2013-10-29 15:23
Peer-Review Started
2013-10-30 21:15
To Make the First Decision
2013-11-13 14:37
Return for Revision
2013-11-14 12:01
Revised
Second Decision
2014-01-20 18:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-01-20 19:28
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-03-05 09:43
Publish the Manuscript Online
2014-03-12 14:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Melatonin for the treatment of irritable bowel syndrome
Manuscript Source Invited Manuscript
All Author List Kewin Tien Ho Siah, Reuben Kong Min Wong and Khek Yu Ho
Funding Agency and Grant Number
Corresponding author Khek Yu Ho, Professor of Medicine, Chief, University Medicine Cluster, National University of Singapore Tower Block, Level 10, 1E Kent Ridge Road, Singapore 119228, Singapore. khek_yu_ho@nuhs.edu.sg
Keywords Melatonin; Irritable bowel syndrome; Pain; Sleep; Analgesia
Core Tip Irritable bowel syndrome (IBS) is a common disorder associated with significant disability and high social cost. This is partly due to lack of effective treatment with low side effects. Melatonin is a drug that was postulated to be a potential useful arsenal in battling IBS. Its role in analgesia has been recognized in several other fields of medicine. Several well-designed placebo-controlled trials in IBS patients had consistently showed improvement of abdominal pain when taking 3 mg of melatonin with no serious side effect. Future studies should examine the long term effect of Melatonin as well as its effect on central nervous system and gut motility.
Publish Date 2014-03-12 14:46
Citation Siah KTH, Wong RKM, Ho KY. Melatonin for the treatment of irritable bowel syndrome. World J Gastroenterol 2014; 20(10): 2492-2498
Url http://www.wjgnet.com/1007-9327/full/v20/i10/2492.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i10.2492
Full Article (PDF) WJG-20-2492.pdf
Full Article (Word) WJG-20-2492.doc
Manuscript File 6850-Review.doc
Answering Reviewers 6850-Answering reviewers.pdf
Copyright License Agreement 6850-Copyright assignment.pdf
Peer-review Report 6850-Peer review(s).pdf
Scientific Editor Work List 6850-Scientific editor work list.doc