Publication Name	World Journal of Gastroenterology
Manuscript ID	6853
Country	South Korea

Received	2013-10-29 15:33
Peer-Review Started	2013-10-30 20:52
To Make the First Decision	2013-12-04 08:48
Return for Revision	2013-12-04 19:43
Revised	2014-01-20 09:20
Second Decision	2014-02-20 09:08
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-02-20 09:25
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-18 09:49
Publish the Manuscript Online	2014-04-17 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Invasive and non-invasive diagnosis of cirrhosis and portal hypertension
Manuscript Source	Invited Manuscript
All Author List	Moon Young Kim, Woo Kyoung Jeong and Soon Koo Baik
Funding Agency and Grant Number
Corresponding Author	Soon Koo Baik, MD, PhD, Professor Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju Severance Christan Hospital, 20, Ilsan-ro, Wonju 220-701, South Korea. baiksk@yonsei.ac.kr
Key Words	Hepatic fibrosis; Portal hypertension; Liver biopsy; Hepatic venous pressure gradient; Non-invasive test; Transient elastography
Core Tip	Chronic liver disease is a heterogeneous and dynamic condition. So, noninvasive exact estimations of the status and changes in hepatic fibrosis and portal hypertension are essential in the management of this disease. Recently, a few tests, such as liver stiffness measurement based on transient elastography (TE) or magnetic resonance have shown promising results in this field. However, the reproducibility of these non-invasive tests needs to be validated in diverse clinical situations and etiologies. Especially, it is important to study about the long term prognostic value of non-invasive tests in hepatic fibrosis and portal hypertension that can leads to new paradigm in the tailored management of chronic liver disease. Notably, the integration of serologic tests with other non-invasive tests, such as TE, allows the progression in the management of patients with chronic liver disease in the future.
Publish Date	2014-04-17 13:27
Citation	Kim MY, Jeong WK, Baik SK. Invasive and non-invasive diagnosis of cirrhosis and portal hypertension. World J Gastroenterol 2014; 20(15): 4300-4315
URL	http://www.wjgnet.com/1007-9327/full/v20/i15/4300.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i15.4300

Full Article (PDF)	WJG-20-4300.pdf
Full Article (Word)	WJG-20-4300.doc
Manuscript File	6853-Review.docx
Answering Reviewers	6853-Answering Reviewers.pdf
Copyright License Agreement	6853-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6853-Language certificate.pdf
Peer-review Report	6853-Peer review.pdf
Scientific Editor Work List	6853-Scientific editor work list.doc